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21 July, 2011 Oral poster discussion session, 6th IAS Conference, Roma PowerPoint Presentation
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Causes of death and risk factors of mortality in HIV-infected patients treated for tuberculosis enrolled in the CAMELIA trial (ANRS 1295/12160 – CIPRA KH001/10425).

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Causes of death and risk factors of mortality in HIV-infected patients treated for tuberculosis enrolled in the CAMELIA trial (ANRS 1295/12160 – CIPRA KH001/10425)

O. Marcy, D. Laureillard, S. Chan, Y. Madec, C. Mayaud, L. Borand, N. Prak, C. Kim, K.K. Lak, C. Hak, B. Dim, T. Sok, A.E. Goldfeld and F.X. Blanc

21 July, 2011

Oral poster discussion session, 6th IAS Conference, Roma

study design
Study design
  • HIV+ patients with AFB+ tuberculosis (TB) and CD4 ≤ 200/mm3
  • TB regimen: 2RHEZ/4RH
  • Randomized to start ART (D4T/3TC/EFV)
    • Early: 2 weeks after TB treatment onset
    • Late: 8 weeks after TB treatment onset
  • Primary endpoint: survival
  • Causes of death were secondarily assessed

ANRS 1295/12160 – CIPRA KH001/10425 study

mortality
Mortality
  • Median follow-up duration: 25 months
  • 149 / 661 (22%) enrolled patients died
  • Place of death:
    • 63 (42%) deaths occurred at home
    • 86 (58%) occurred in hospital

ANRS 1295/12160 – CIPRA KH001/10425 study

causes of death
Causes of death

ANRS 1295/12160 – CIPRA KH001/10425 study