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NSF Directorate for Engineering | Division of Chemical, Bioengineering, Environmental, and Transport Systems ( CBET ) Transport and Thermal Fluids Cluster Particulate and Multiphase Processes ( PMP ) Program Director - Marc Ingber - mingber @ nsf.gov. Research Focus and Examples
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Chemical, Bioengineering, Environmental, and Transport Systems (CBET)
Transport and Thermal Fluids Cluster
Multiphase Processes (PMP)
Program Director - Marc Ingber - firstname.lastname@example.org
Research Focus and Examples
Current Research Focus
Typical PMP Projects
MULTIPHASE FLOW PHENOMENA & MICROSTRUCTURED FLUIDS(20%)
Bubble/droplet dynamics; emulsions; particle-laden flows; multiphase flows in
microfluidic devices; colloids, self and directed assembly; materials processing
Production of particles with engineered characteristics, unique composition, and
surface properties; particle assembly into functional structures, sensors, and
devices; particle tagging
Separation processes; force chains; modeling, DEM simulations; lubrication;
powder flows; effects of cohesion; pharmaceutical and neutraceutical processing
Processes leading to new technologies for environmental sustainability; sediment
transport; avalanches; plumes; viscous resuspension; fate and transport of
MULTIPHASE TRANSPORT IN BIOLOGICAL SYSTEMS(20%)
Multiphase transport in biological systems with applications to clinical diagnostics
and therapeutics; lab-on-a-chip; drug delivery; drug discovery
The following slides depict some typical PMP research efforts
Novel templating nanofabrication platform
Mimics antireflective moth eyes
Mimics superhydrophobic cicada
Spin-coated colloidal crystals with
remarkably large domain sizes and
unusual nonclose-packed structures
Peng Jiang - University of Florida
and Ultrasound Radation
Alberto Aliseda - University of Washington
Methodology can also be used to treat tumors and prevent strokes
Applications of Pickering Emulsions
Lenore Dai - Arizona State University
SEM Images with X-ray Microanalysis
In contrast to conventional emulsions using surfactants
as stabilizers, Pickering emulsions use solid particles.
Provide a novel method to synthesize core-shell latexes
through one-step Pickering emulsion polymerization.
Successfully synthesized silica-polystryrene composite
latexes using Pickering emulsions as a template.
Inclusion of nanoparticles has a strong effect on the
size distribution of the composite-latexes.
Additional surfactants either inhibit nanoparticle
interfacial assembly or even latex formation.
Novel and simple methods to synthesize functional
Unique class of materials that have wide potential
Nina Schapley - Rutgers University
The following specific aims support the Project Goal:
Synthesizing biopolimer microbeads coated with
complementary biopolymer nanoparticles and
characterizing equilibrium heavy metal ion uptake
by the combined structures.
Understanding mechanisms of particle size separation
in a bimodal suspension flowing through expansion,
contraction and bifurcation geometries, affecting the
arrangement of microparticles when a fixed bed is
formed. (See Figure 1.)
Quantifying the kinetics of metal ion adsorption in flow
through a fixed bed of biopolymer micro-nanoparticle
structures, and hence gaining insight into the dominant
mass transfer processes.
Carlos Rinaldi - University of Puerto Rico-Mayaguez
Uniform hyperthermia at the tumor site
Inject and forget treatment
High circulation lifetime
Permeable through tumor leaky vasculature
Avoid non-specific interactions with
blood and tissues
Functionalized nanoparticles may target
specific cell types (cancerous vs. healthy)
Minimize damage to surrounding healthytissue
~ 46° C
of “Patchy” Particles
Ilona Kretzschmar - The City College of New York
Q = 2º
guidelines for binding energies, particle concentrations, and patch sizes
patches of different geometry obtainable