10.3 Regulating the Cell Cycle

1. 10.3 Regulating the Cell Cycle p286

2. Q: How is the cell cycle regulated? • A: The cell cycle is controlled by regulatory proteins both inside & outside the cell.

3. Regulatory Proteins • Internal regulators • External regulators • Cyclin-regulates the timing of the cell cycle. • Normally, when cells touch, they stop growing. • Growth factors-one of a group of external regulatory proteins that stimulate the growth and division of cells.

4. Apoptosis-Process of programmed cell death.

5. Cancer: Uncontrolled Cell Growth p53 gene • Q: How do cancer cells differ from other cells? • A: Cancer cells do not respond to the signals that regulate the growth of most cells. As a result, the cells divide uncontrollably.

6. Cancer: Uncontrolled Cell Growth • Cancer-does not respond to the signals that regulate the growth of most cells. • Tumor-mass of cancer cells. • Caused by defects in the genes that regulate cell growth & division (p53 gene).

7. WB p150-152 • Skip #9, 10, 12, 14