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Genetic Diagnosis and Consent Process for Cleft Lip and Palate Patients

Ensure information on DNA collection and consent is properly provided to parents and patients by the cleft team in coordination with the national cleft centre and Crane team. Options for blood and saliva DNA testing at the outpatient clinic are explained clearly.

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Genetic Diagnosis and Consent Process for Cleft Lip and Palate Patients

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  1. Diagnosis made Antenatal Postnatal Consent Consent Cleft team inform national cleft centre and Crane Cleft team inform national cleft centre and Crane Cord blood taken yes no DNA / Cell line Blood taken by phlebotomy at time of primary closure Blood taken from parents by phlebotomy at outpatient clinic Blood taken from parents by phlebotomy at outpatient clinic yes no yes no DNA / Cell line no yes Saliva buccal cell DNA collection DNA / Cell line Blood taken from child by phlebotomy at outpatient clinic Saliva buccal cell DNA collection DNA / Cell line yes no Saliva buccal cell DNA collection DNA / Cell line Blue = DNA from child, Red = DNA from parents

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