1 / 10

Cardio and Digestive Herbs Cont.

Cardio and Digestive Herbs Cont. Chamomile, Horse chestnut, Licorice, Spices. Chamomile ( Matricaria recutita). Actions: Anti-inflammatory, antiseptic, sedative, antispasmodic.

alvaro
Download Presentation

Cardio and Digestive Herbs Cont.

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. Cardio and Digestive Herbs Cont. Chamomile, Horse chestnut, Licorice, Spices

  2. Chamomile (Matricaria recutita) • Actions: Anti-inflammatory, antiseptic, sedative, antispasmodic. • Medicinal Uses: Gastrointestinal disorders. Calming and sedative effect general relaxation. Children’s cold, eye wash, skin treatment. • Side effects: low • Dose: 1-3 teaspoon decoction tincture 1-4 ml in a cup water oil:1-2 drop (1:50 dilution)

  3. Chemistry, Functions, Toxicity • Volatile oils: α-bisabolol, chamazulene, (↓ inflammation, fever) flavonoids: apeginin, luteolin, quercetin (inflammation, sedative, antioxidant) • CNS action is through benzodiazepine receptors • Orally used to treat diarrhea, anxiety, restlessness, flatulence , teas mainly used for sedation or relaxation. • Topically reduce inflammation, induce healing of wounds and burns • Toxicity: contact dermatitis, allergic reactions GI; nausea, vomiting Anaphylaxis in case of extreme sensitivity

  4. Herb –Drug Interaction Antiplatelet and anticoagulants (warfarin, aspirin, heparin, NSAIDs, clopidogrel, eptifibatide, tirofiban, ticlopidine, dipyridamole and COX-2 inhibitors

  5. Horse Chestnut(Aesculus hippocastanum) • Traditionally used for chronic venous insufficiency (CVI). Other properties: analgesic, anticoagulant, astringent and expectorant. • The medicinal parts of horse chestnut include the dried leaves, the oil extracted from the peeled nuts, and the dried chestnut seeds. • The seeds of horse chestnut contain a saponin mixture: aescin (or escin) and prosapogenin. • Other compounds: rutin and quercitrin and coumarins. • The extract is used as conjunctive treatments for lymphedema, hemorrhoids, BPH. • Dose: 250mg (high dose up to 750mg, tincture: 1-4ml

  6. Functions • The 3 types of pharmacodynamic actions that have been attributed to escin include anti-edematous properties, anti-inflammatory activities, and venotonic properties. • Aescin works on the capillary membrane, normalizing vascular permeability. This then may reduce the outflow of fluid into the extracapillary space. • Anti-inflammatory properties suggest that escin can interfere with the cellular phase of the inflammatory process, i.e. with leukocyte activation. The accumulation of leukocytes in CVI-affected limbs with their subsequent activation is considered an important patho-physiological mechanism of CVI.

  7. Herb –Drug Interaction • Anticoagulants: may increase anticoagulant effect • Antidiabetic, insulin: Increased hypoglycemic effect • Drugs that are highly protein bound: Aescin binds to plasma proteins and may displace these drugs. • Potential synergetic effect with other anticoagulant and hypoglycemic herbs.

  8. Licorice (Glycyrrhiza glabra ) • Traditionally used for peptic ulcer, additionally antiviral, anti-inflammatory, antitussive, and additive in many formulations. • Licorice root contains water-soluble triterpenoid glycoside glycyrrhizin, isoflavans hispaglabrin A and B, glabridin and other phenolic constituents. • Commonly used as a sweetening/flavoring agent to counteract the unpleasant taste of many drugs • Dosage: 200 mg glycyrrhizin daily

  9. Functions, Toxicity • Glycyrrhizin is a sweetener, used by the food/drug industry • Glycyrrhetenic acid inhibits 11-beta-hydroxydehydrogenase that prevent cortisol from acting as a mineralcoid. ( leading to sodium and water retention and potassium excretion) • Toxicity: CNS numbness, paralysis CV; hypertension, arrhytmias, heart failure metabolic: hypokalemia, hypernatremia musculoskeletal: myopathy, musclecramps

  10. Herb –Drug Interaction • Antiarrhytmics: Hypokalemia, Torsades de Pointes • Antihypertensives:less effective • Corticosteroids: additive effect • Digoxin: increased toxicity • Diuretics: may worsen hypokalemia

More Related