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Autonomic Nervous System. Medical Neuroscience Dr. Wiegand. Autonomic Nervous System. Enteric System Sympathetic Nervous System Parasympathetic Nervous System All systems have GVE and GVA components Primarily considered a two neuron chain motor system. Limbic System. Hypothalamus.

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autonomic nervous system

Autonomic Nervous System

Medical Neuroscience

Dr. Wiegand

autonomic nervous system1
Autonomic Nervous System
  • Enteric System
  • Sympathetic Nervous System
  • Parasympathetic Nervous System

All systems have GVE and GVA components

Primarily considered a

two neuron chain motor system

slide3

Limbic System

Hypothalamus

Afferent Input (GVA)

Autonomic Nervous System

Reticular Formation

Spinal Level

Periphery

Autonomic Nervous System

psns sns similarities

“B” fiber

“C” fiber

Nuclei

Acetylcholine

Ganglia

Spinal cord

or brainstem

Periphery

PSNS & SNS – Similarities
psns sns differences
SNS

activate body

thoracolumbar (T1-L2)

short preganglionic/long postganglionic fibers

global responses

postganglionic transmitter: norepinephrine (except sweat glands – ACH)

PSNS

prepare body for rest

craniosacral (CN III, VII, IX, X & S2-4)

long preganglionics/short postganglionic fibers

discrete/local responses

postganglionic transmitter: acetylcholine

PSNS & SNS – Differences
sympathetic nervous system
Sympathetic Nervous System
  • “Fight or Flight” system
  • Activation
    • increases heart rate
    • increases sweating
    • dilates pupil
    • inhibits GI movement
    • closes sphincters
    • diverts blood from skin and GI tract to skeletal muscles
sympathetic nervous system preganglionic neuron may
Sympathetic Nervous System- Preganglionic Neuron May:
  • terminate on postganglionic neuron in the sympathetic chain ganglia
  • ascend or descend to higher or lower ganglia and terminate on postganglionic neuron in the sympathetic chain ganglia
  • pass through the sympathetic chain to prevertebral ganglia (celiac, inferior or superior mesenteric)
  • pass through the sympathetic chain ganglia to adrenal medulla
slide11

referred pain

  • heart – T1-4
  • gall bladder – T6-8
  • stomach – T7-8
slide13
preganglionic fibers from T1-5 ascend

postganglionic fibers from sup. cervical ganglia follow carotid a.

fibers follow III and V ophthalmic

innervate dilator m, levator palpebrae, sweat & lacrimal glands

parasympathetic nervous system
Parasympathetic Nervous System
  • prepares body for rest
    • promotes digestion, GI peristalsis
    • slows heart rate
    • constricts pupil
    • empties bladder
    • relaxes sphincters
    • mediates genital erection
horner s syndrome
Horner’s Syndrome
  • damage to the descending fibers from the hypothalamus or the superior cervical ganglia
  • miosis – pupillary constriction
  • anhidrosis – lack of sweating
  • ptosis – drooping of the eye lid
  • enophthalmos – eye appears to sink in to the orbit
bladder
Bladder
  • SNS – retention
  • PSNS – voiding (micturation)
slide18

L1 – L2 GVE

  • SNS input from L1-2 (int. urinary sphincter)
  • PSNS input from S2-4 (detrusor mm)
  • GSE (Onuf) to ext. urinary sphincter
  • GSA (pain, temp & pressure to T12/L1 & S2-4
  • GVA to S2-4
  • paracentral lobule & brainstem

S2 – S4 GVE

S2 – S4 GSE

S2-4 GVA/GSA

(T12/L1)

autonomic nervous system and the bladder
Autonomic Nervous System and the Bladder
  • “UMN bladder” = “spastic bladder” = automatic reflex bladder
  • “LMN bladder” = “flaccid bladder” = “atonic bladder” = autonomous reflex bladder