Chapter 15: The Chromosomal Basis of Inheritance. Law of Independent Assortment. Alleles on nonhomologous chromosomes separate independently during gamete formation. Thomas Hunt Morgan In early 1900’s used fruit flies and figured out the concept of linked genes Symbols
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Alleles on nonhomologous chromosomes separate independently during gamete formation.
+ = wildtype (normal)
b+ = gray body (wildtype)
b = black body
vg+ = normal wings (wildtype)
vg = vestigial wings (small)
Cross: b+bvg+vg x bbvgvg
If you actually perform the cross on the prior slide and you do not get the expected 1:1:1:1 ratio in the offspring, this indicates gene linkage and possibly crossovers!
The Punnett square would have to include 4 different possible sex cells for mommy (the non-crossovers and the crossover scenarios). The bold genotypes are the result of crossovers.
In fruit flies, white eyes are recessive and sex-linked while red eyes are dominant. Cross a red-eyed female (whose father had white eyes) with a white-eyed male. What are the possible offspring? Include gender in your answer.