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This study analyzes nuclear CLIC4 in relation to P53, including figures on tissue array analysis and Ha-tag analysis of CLIC4 with Actin. The experiments investigate the impact of various treatments on CLIC4 levels and localization. The results provide insights into CLIC4 dynamics in response to different stimuli and genetic variations.
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Supplementary Figure 1 A B No Treatment Null 12h P53 12h No Treatment Null 12h P53 12h SP1 308 p53 CLIC4 Ponceau PAM 212 SCC 13 p53 CLIC4 Ponceau
Supplementary Figure 2 Tissue array analysis of nuclear CLIC4 Immunohistochemistry 0 2+ 4+ 3-4+
Supplemental Fig. 3 Hr KGF 0 0.5 1 2 6 8 16 32 CLIC4 CD1 Actin A
P Ha-CLIC4 Dox - + - exo endo Actin Genotype WT TR CLIC4 Actin Supplementary Figure 4 A CLIC4 Ha-tag B Exo 1 2 3 4 5 6 7 8 9 10 11 12 13 14 N CLIC4 Endo Actin C