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Analyzing Genetic Sequences: Insights from Advanced Bioinformatics Techniques

This document delves into genetic sequences, providing a comprehensive analysis using advanced bioinformatics techniques. It examines specific sequences, their structures, and annotations including transcription factors like NF-κβ and AP1, along with associated energy changes (ΔG). The information is critical for understanding gene regulation mechanisms and applications in genetic research and therapy. Detailed attention is given to various sequence components and predicted interactions, emphasizing the role of bioinformatics in modern genetics.

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Analyzing Genetic Sequences: Insights from Advanced Bioinformatics Techniques

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  1. A 10 20 30 40 50 60 70 80 90 ....|....| ....| ....| ....|....| ....|....| ....|....| ....|....| ....|....| ....|....| ....|....| B(LAI)TCCGGAGTAC TTCAAGA.... .......... .........A CTGCTGACAT CGAGCTTGCT ACAA...GGG ACTTTCCGCT GGGGACTTT X ---------- -A---AG.... .......... .........- -------TGA A--AG--T-- -AC...T--- ---------- --------- B1 ------A--- -A---AG.... .......... .........- ----C----- ----.--T--- ---..G--- ---------- --------- B2_S ------A--T -A---AG.... .......... .........- ---------- ----.--T--- ---..G--- ---------- --------- B2_L --------TT -A-----ACTG CTGACGTCGA GTTACAGGG- ---------- ---A---T-CG --...G--- ---------- --------- AE ------A--- -AT--AG.... .......... .........- ---------A A--AG--T--- AC...TAA- ----.----- --------- 100 110 120 130 140 150 160 170 180 ....|....| ....|....| ....|....| ....|....| ....|....| ....|....| ....|....| ....|....| ....|....| B(LAI)CCA.GGGAGG CGTGGCCTGG GCGGGACT.G GGGAGTGGCG AGCCCTCAGA TCCTGCATAT AAGCAGCTGC TTTTTGCCTG TACTGGGTCT X ---.------ T--TA----- -----GT-.- ---------T -A-------- -G-------- -------C-- ----C--T-- ---------- B1 ---A------ T--------- --------.- ---------- ---------- -G-------- ---------- ---------- ---------- B2_S ---A------ T--------- --------.- ---------- ---------- -G-------- ---------- ----.----- ---------- B2_L ---.-A---- ----A-A--- --------.- ---------- -A-------- -G-------- ---------- ----.----- ---------- AE ---G------ T------G-- -T--AGT-.- --------TT -A-------- -G-------A -------C-- ----C--T-- ---------- 190 200 210 220 230 240 ....|....| ....|....| ....|....| ....|....| ....|....|....|....| ... B(LAI)CTCTGGTTAG ACCAGATCTG AGCCTGGGAG CTCTCTGGCT AACTAGGGAACCCACTGCTT AAG X ----A----- ---------- ---------- ---------- -G------------------ --- B1 ---------- --------A- ---------- ---------- G------------------- --- B2_S ---------- --------A- ---------- ---------- G------------------- --- B2_L ---------- ---------- ---------- ---------- -G------------------ --- AE ----T----- -----G--.- ----C----- ---------- -G-A---------------- --- BseAI TATAA-136 RBE III NF-κβII NF-κβI GABP AP1 SP1III SP1II SP1I CATATAA-30 E +1 BfrI CACCC-bi B C B (LAI) AE B1 B2_S B2_L X G G G G G G G G G G U U U U U G G G G G A A A A A C C C C C G G U G U U A C A A C C C C C U U U U U U U U A A A A A A C C C C C G C ∆G = -29.6 ∆G = -29.9 ∆G = -29.7 ∆G = -29.6 ∆G = -29.0 C ∆G = -29.7 C G U A U U U U C G U G G G A A U U G G C A G G G C G U C G U C A A G U G C C A A C U C G C G G G G C A G G C U G C C G U C A G C A U A C C A G U G U C U C U G G U U A G C U U U C U U C G C G C A G A C G A G G U G C A G G C C U G U U C G C U G G G A U U U C C A C G G A A A G C G U U U G G A U U C U A G C C C G G G U U C G U A G G G G U C C C A A C G C G A C A G G G C G A U G C C G U A C A G U G C U U G C C G U U U A G U G G C C C C A A A C A G C C U G C C U U U C A G G A G A A G G C G C A A U C G U G G C C C A C G U U G G A C G G U G G G G C U G C C C U C A U A U A

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