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nanotheratics n1 project

The Nanotheranostics u2013 NT1 project concerns the treatment of skin cancer using plasmonic thermal phototherapy, which activates surface plasmons to generate hyperthermia. The product is a class 3 medical device made of gold nanoparticles designed using green chemistry, and clinical investigations are due to begin shortly

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nanotheratics n1 project

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  1. The Nanotheranostics – NT1 project www.torskal.com

  2. What is the Nanotheranostics – NT1 project? The Nanotheranostics – NT1 project concerns the treatment of skin cancer using plasmonic thermal phototherapy, which activates surface plasmons to generate hyperthermia. The product is a class 3 medical device made of gold nanoparticles designed using green chemistry, and clinical investigations are due to begin shortly. www.torskal.com

  3. Need for Innovative Treatment Challenges with Current Treatments: Surgery leaves scars and disfiguration. Melanoma requires immediate intervention. Chemotherapy and radiation cause side effects. Solution: Photothermal Therapy (PTT) using Gold Nanoparticles Targeted treatment with minimal side effects. Selective tumor destruction without damaging healthy tissue. www.torskal.com

  4. How Photothermal Therapy (PTT) Works? Mechanism: Uses light-sensitive gold nanoparticles (AuNPs). Near-Infrared (NIR) laser activates gold nanoparticles. Local heat (7°C increase) induces tumor cell death. Advantages: Minimally invasive. Reduces side effects compared to chemotherapy/radiation. Selective targeting ensures healthy tissues remain unaffected. www.torskal.com

  5. The Green Chemistry Approach • Green Synthesis of Gold Nanoparticles • Uses Hubertia ambavilla, an endemic plant from Réunion Island. • No toxic chemicals involved. • Patented process for eco-friendly nanoparticle synthesis. • Why Gold Nanoparticles? • Biocompatible and non-toxic. • Easily internalized by cancer cells. • Highly efficient in converting light to heat. www.torskal.com

  6. NT1 – Clinical & Preclinical Validation • Preclinical Studies Results: • No toxicity observed at any level. • Effective anti-tumor activity in vitro and in vivo. • Preferential internalization into cancer cells. • Cells die via apoptosis (not necrosis) → reduces inflammation. • Current Status: • Clinical trials starting soon. • Systemic and local administration optimized. www.torskal.com

  7. Project Funding & Collaborations Co-financed by: European Union & Réunion Region (FEDER 1.15, 1.16). MESR (CIR) & BPI France (recoverable advance). Postdoctoral research supported under the same program. Torskal – Pioneering Green Nanomedicine. www.torskal.com

  8. Conclusion & Future Outlook NT1 – A Revolutionary Step in Skin Cancer Therapy One-time injection therapy. Fewer side effects than traditional treatments. Sustainable and eco-friendly nanotechnology. Contact Information: Website: www.torskal.com Email: contact@torskal.com Address: 2 rue Maxime Rivière, Sainte Clotilde, 97490, La Réunion, France

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