Animal Welfare Training. The Development Process. Remember This!. Computer Models Chemical Models In-Vitro Models In-Vivo Models Human Models. The Drug Development Process. Is it safe? Does it work?. Compound X. How much? How often? How should it be put
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Is it safe?
Does it work?
How should it be put
into the body?How long does it stay there?
Are the effects: short and long?
Does it leave the body? How?
Does the body change it? How?
Do other variables matter?
Contract Research Organization
USDA United States Department of Agriculture
NIH National Institutes of Health
IACUC Institutional Care and Use Committee
The State Massachusetts Department of Public Health
Massachusetts Society for Prevention of Cruelty to Animals
AAALAC Association for Assessment and Accreditation of
Laboratory Animal Care International
The company must investigate/report to the IACUC. IACUC
will review the response and investigate too. IACUC will
report findings/recommendations to the Institutional Official.
The outcome is variable, but serious violations (abuse, neglect) will result in termination(s).