Scleroderma Preloader

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Clinical Manifestations. Skin InvolvementVascular DiseaseOrgan Involvement. Skin Involvement. Characterized by variable thickening and hardening of the skin- pruritus in the early stages- edema in the early stages- sclerodactyly- digital ulcers- pitting at the fingertips- telangiectasia- calcinosis cutis.

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