Ischemic Heart Disease. Dr. Fletcher. Week 3/ CVS module 9-11-2003. Ischemia heart disease. Restriction of blood supply, relative to demands of the heart. Ischein = to restrict. Recall: Heart has high : - Work load. - Metabolic Rate. - Aerobic metabolism.
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Week 3/ CVS module
- Metabolic Rate.
- Aerobic metabolism.
- Oxygen demands.
Stenosis Narrowing of blood vessle
Cardiac lesions Ischemia fibrosis.
Cardiac lesions Infarct (necrosis).
Pain : Infarct Pain
Closure of the lumen
1) Induced by exertion.
2)Paroxysmal (~ 15 minutes) (to differentiate between it and other chest pain).
3) Relieved by rest.
4) Relieved by Nitroglycerin vasodilatations.
1) Very sever.
2) Prolonged pain - at least 30 min (not 15 min)
- often 1 hours.
- Some cases 6 hrs ( have to be controlled byopiates).
3) Not induced by exertion.
4) Not relieved by rest.
5) Not relieved by nitroglycerin.
Arrhythmia due to Ischemia ( local) of conducting system.
it can be picked up by ECG
& might end up with sudden death.
We see – Grayish-white sheen.
- ill defined Vague
1) Arrhythmia Ventricular fibrillation.
2) Ischemia : a) re-entrant circuit
b) damaged conducting system, coronary lesions (hard to find).
3) Massive Acute infarct: infarct is not visible but coronary thrombosis easily found.