Selecting for Favorable Genetic Response to Disease Gary Snowder, PhD Research Geneticist USDA, ARS, USMARC Outline Justification Challenges Current research on Genetic Resistance to BRD and IBK Justifications for Genetic Selection Justifications
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Gary Snowder, PhD
USDA, ARS, USMARC
E. Kanis*,2, K. H. De Greef , A. Hiemstra*,3 and J. A. M. van Arendonk†
*Animal Breeding and Genetics Group, Wageningen University, 6700 AH Wageningen, The Netherlands; and
†Animal Sciences Group, 8200 AB Lelystad, The Netherlands 2
J. Anim. Sci. 2005, 83:948-957
Consumers expect meat animals raised with better welfare, produced in an environmentally friendly manner and,
free of feed “additives”, antibiotics, and vaccines.
Only the nervous system is more complex.
More complex than reproduction, growth, lactation, or feed efficiency.
● Many factors influence disease resistance.
Calf Pneumonia caused by:
VirusesInfectious Bovine Rhinotracheitis (IBR), Bovine Viral Diarrhea (BVD), Bovine Respiratory Syncytial (BRS), and Parainfluenza 3 (PI3)
Bacteria(Mannheimia haemolytica, Pasteurella multocida, Haemophilus somnus)
PATHOGENS + STRESS = DISEASE
Genetic research of human diseases, especially molecular genetics, is far ahead of livestock research.
Genetically Resistance to:
Somatic Cell Score .15
Respiratory .11 to .48
Current research on the influence of genetics on resistance to BRD and IBK
Mar20 Apr19 May19 June18 July18 Aug17 Sept16 Oct16
Incidence of IBK by Date
Range 0.00 to 0.28
Low to Moderate heritability
Crossbred calves from tropically adapted sires had a significantly lower incidence of IBK
Moderate genetic component to resistance to BRD
Range: 5 - 44%; Avg. 17%
Agrees with Loneragan (2001) and Schunicht et al. (2003)