The evolution of antibiotic resistance. Rob Knell / Lars Chittka. MRSA in the UK. Deaths per year. Source: Health Protection Agency. MRSA - Methicillin resistant Staphylococcus aureus. - S. aureus is a common bacterium that can be found on the skin of many healthy people
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Source: Health Protection Agency
"There was complacency in the 1980s. The perception was that we had licked the bacterial infection problem. Drug companies weren't working on new agents. They were concentrating on other areas, such as viral infections. In the meantime, resistance increased to a number of commonly used antibiotics, possibly related to overuse of antibiotics. In the 1990s, we've come to a point for certain infections that we don't have agents available."
Michael Blum, M.D., medical officer in the Food and Drug Administration's division of anti-infective drug products. Quoted in Lewis, R. (1995)The Rise of Antibiotic-Resistant Infections. Available online at
Imipenem resistant Pseudomonas aeruginosae
Streptococcus pneumoniae resistance to penicillins
MRSA penicillin binding protein PBP2A
Hawkey, P. M BMJ 1998;317:657-660