Cizumab 400mg Injection

1. Introduction to Cizumab 400 mg Injection Cizumab 400 Solution for Infusion is an anticancer medication. It is used in the treatment of cancer of colon and rectum, non-small cell lung cancer, kidney cancer, brain tumour, ovarian and cervical cancer. It helps to prevent the growth of new blood vessels that feed tumours and stops tumours from growing.

2. Cizumab 400 Solution for Infusion is an effective medicine, first-line option when used together with other cancer medicines. It is given as an infusion. That means you get it through a small needle in your vein or through a port, which is a device placed under your skin. The doctor will decide your dose and duration and will check you for signs of an infusion reaction such as high blood pressure and trouble breathing. You keep taking Cizumab 400 Solution for Infusion as long as your disease is controlled and your side effects are manageable. Your doctor will determine whether you should stop taking it or not. You may be advised to check blood pressure and levels of protein in urine while you are taking this medication. The most common side effects of this medicine include rectal bleeding, taste change, and headache. Inform your doctor that you are taking this medication before undergoing any surgical procedure, as the drug has the ability to lower the ability of wound healing. Other than this, it also enhances your risk of bleeding thus if you notice any unusual bleeding or bleeding consult with your doctor immediately. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. Uses of Cizumab 400 mg ● ● ● ● ● ● Cancer of colon and rectum Non-small cell lung cancer Kidney cancer Brain tumour Ovarian cancer Cervical cancer How Does Cizumab 400 Works Cizumab 400 Solution for Infusion is an anti-angiogenic medication. It works by blocking a protein called vascular endothelial growth factor (VEGF). This stops the formation of blood vessels that bring oxygen and nutrients to cancerous cells. Side Effects of Cizumab 400 ● ● ● ● ● Black or Tarry stools Bleeding gums Body aches or Pain Burning, tingling, numbness in the arms and feet Chest pain

3. ● ● ● ● ● ● Chills Cloudy urine Decreased urine output Dilated neck veins Fever Irregular breathing Common Side Effects ● ● ● ● ● ● ● ● Fatigue: Feeling tired or weak. Nausea: Feeling the urge to vomit. Loss of Appetite: Decreased desire to eat. High Blood Pressure: Increased blood pressure levels. Proteinuria: Presence of protein in the urine. Headache: Pain or discomfort in the head. Nosebleeds: Occurrence of bleeding from the nose. Mouth Sores: Painful sores or ulcers in the mouth. Serious Side Effects ● ● ● ● ● ● ● Severe Bleeding Hypertension Blood Clots Impaired Wound Healing Gastrointestinal Perforation Proteinuria Impaired Kidney Function Rare Side Effects ● ● ● ● ● ● ● ● ● ● ● ● Wound Healing Complications Thrombotic Microangiopathy (TMA) Posterior Reversible Encephalopathy Syndrome (PRES) Haemorrhage Necrotizing Fasciitis Hypersensitivity Reactions Gastrointestinal Fistula Pulmonary Haemorrhage Hypertensive Crisis Thrombosis Hemoptysis Rhabdomyolysis Dosage of Cizumab 400 mg

4. Cizumab 400 mg Injection contains an active ingredient, Bevacizumab, which is used in the treatment of Cancer of colon & rectum, Non-small cell lung cancer, Brain tumour, Kidney cancer, Ovarian Cancer, Glioblastoma Multiforme, Cervical cancer, Peritoneal Cancer, Fallopian Tube Cancer. This medicine is obtainable in different substitutes & strengths & has got to be purchased or taken on doctor’s prescription only. You must talk with your physician for adjust the dosage & time of the medicine since age & severity of the disease differ from person to person, and this can only be judged by your doctor. Adults are advised to take Cizumab 400 mg Injection at a fixed time with or without food as instructed by your Doctor. You must take Cizumab 400 mg Injection regularly on time for better results. How to Manage Side Effects ● ● ● ● ● ● ● ● Wound Healing Complications Thrombotic Microangiopathy (TMA) Posterior Reversible Encephalopathy Syndrome (PRES) Haemorrhage Necrotizing Fasciitis Hypersensitivity Reactions Gastrointestinal Fistula Pulmonary Haemorrhage Warning & Precautions ● ● ● Allergy Kidney/ Liver disease Cizumab 400 mg Injection is not suggested for use in children below 18 years of age You have to use a consistent contraceptive method to avoid pregnancy while you are on this medication as it can cause birth defects You have to regularly get your blood tests done to examine your blood cells, liver & kidney function, & electrolyte levels during treatment with this medicine You must also get your blood pressure and levels of proteins in urine checked regularly while taking this medicine You should not obtain this medicine if you are pregnant, planning to conceive or breastfeeding You must not drive or operate heavy machines at the same time as taking this medicine as it may cause dizziness Always talk with your medical doctor straight away to get the most excellent possible treatment if you are observing several of the above mentioned conditions. ● ● ● ● ● ●

5. Safety Advice ● Prescription Only: If “Cizumab 400” is a medication, it should only be taken with a valid prescription from a qualified healthcare provider. Inform Your Doctor: Provide your healthcare provider with a detailed medical history, including any pre-existing medical conditions, allergies, or previous reactions to medications. Pregnancy and Breastfeeding: If you are pregnant or breastfeeding, discuss the potential risks and benefits of taking “Cizumab 400” with your doctor before starting treatment. Dosage Compliance: Take “Cizumab 400” exactly as prescribed by your doctor. Do not change the dosage or frequency without their approval. ● ● ● FAQs 1. What kinds of cancer can Cizumab 400 Solution for Infusion be used for ? Ans. Cizumab 400 Solution for Infusion is approved for the treatment of cancer of the colon or rectum that has spread to other parts of the body. It must be given along with chemotherapy. Other types of cancers that it helps with includes certain types of lung cancer, kidney cancer, ovarian cancer, cervical cancer, and glioblastoma (a type of brain tumour). 2. How is Cizumab 400 Solution for Infusion given? Ans. Cizumab 400 Solution for Infusion is given as an infusion. That means you get it through a small needle in your vein or through a port, which is a device placed under your skin. Your doctor will decide your dose and duration and will monitor you for signs of an infusion reaction. 3. How long can I take Cizumab 400 Solution for Infusion for? Ans. You keep taking Cizumab 400 Solution for Infusion as long as your disease is controlled and your side effects are manageable. Your doctor will determine whether you should stop taking Cizumab 400 Solution for Infusion. If your cancer progresses during this initial treatment, talk to your doctor if a different chemotherapy may be an option. 4. How does Cizumab 400 Solution for Infusion work differently from chemotherapy? Ans. Chemotherapy attacks fast-growing cells, like cancer cells. In contrast, the purpose of Cizumab 400 Solution for Infusion is to prevent the growth of new blood vessels that feed tumours. This causes the tumour to shrink, or to stop growing.