CRITICAL PERIOD. Modified from MacLusky and Naftolin Science 1981; 211:1294 - 1303. OH. Testosterone. O. Aromatase. 5 a - Reductase. OH. HO. O. Estradiol. 5 a - DHT. Androgen-dependent sexual dimorphism in the CNS. Ultrastructural differences Neuronal nuclear and nucleolar size
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Modified from MacLusky and Naftolin Science 1981; 211:1294 - 1303
5a - Reductase
5a - DHT
Arnold and Gorski 1984
10 20 30 12 36 60 Age (weeks) Time (hr)