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Normal urothelium. Cell layers. Urothelium = all epithelial cells. Superficial/umbrella Intermediate 2 to >10 cells Basal . Normal urothelial mucosa. Mucosa = Urothelium + stroma beneath urothelium deep to muscularis mucosae. Normal urothelial mucosa. Normal urothelial mucosa.

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Cell layers l.jpg

Normal urothelium

Cell layers

Urothelium = all epithelial cells

  • Superficial/umbrella

  • Intermediate

    • 2 to >10 cells

  • Basal


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Normal urothelial mucosa

Mucosa = Urothelium + stroma beneath urothelium deep to muscularis mucosae



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Normal urothelial mucosa

Brunn’s nests

Urothelium

Mucosa

Muscularis mucosae


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Normal urothelial mucosa

Urothelium

Cystitis cystica

Mucosa

Muscularis mucosae


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Muscularis mucosae

Urothelium

Lamina propria

Mucosa

Submucosa

Lymphoid nodule

Muscularis propria


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Muscularis mucosae

Distribution of muscularis mucosae (as % of bladders)

Prominent & continuous 3 %

Discontinuous & interrupted 20 %

Scattered & dispersed 71 %

Absent 6 %

Muscularis propria


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Pathologic staging of bladder tumors

Ta and Tis tumors

T1 tumors

T2 tumors