steps towards sch503034 boceprevir. a ns3 Preloader

steps towards sch503034 boceprevir. a ns3 - PowerPoint PPT Presentation


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The HCV Life Cycle. . NS3 Protease. NS3. . . . . . . . . . . . Positive strand RNA virusGenome encodes a single polyproteinNS3 cleaves 4 downstream sitesSerine protease Active site shallow and hydrophobic. HCV Genome Organization. Structural Proteins. NS3 protease inhibitors. hydrolysis. Electrophilic inhibition.

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