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Optimization of Antibiotic Therapy and Monitoring of Antibiotic Resistance in the Karaganda Region of Kazakhstan. Karaganda. Kazakhstan population is 15000000 people Karaganda region population is 1.5 mil Karaganda region 428 thousand sq. km.
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Kazakhstan population is 15000000 peopleKaraganda region population is 1.5 milKaraganda region 428 thousand sq. km.
This slide doesn`t reflect real picture
of antibiotic resistance level
(Initiator of formulary system inculcation in Karaganda region became drug information center)
The main criteria during antibiotic purchase is price, but not quality.
Doesn't determine biological availability and biological equivalence of drugs during purchase.
Tasks of research
Research retrospective, randomized, cases in outpatient and hospital departments were analyzed
The first antibiotic use research patients with acute bronchitis and ARD, cases in outpatient and hospital departments were analyzed 20 outpatient case histories of adult patients and in every of 63 primary health departments (PHD), (45 PHD in Karaganda, 10 PHD in Zhezkazgan, 8 PHD in Satpaev) were chosen by means of randomized collection in 4 quarter 2002 and in 4 quarter 2003
The second antibiotic use research was performed in surgical departments of multiple-discipline state hospital(60 beds) and private surgical hospital (45 beds) 300 case histories of patients in 2000 and 300 in 2003 in every of two hospitals were chosen.
10 outpatient case histories patients with ARD and ten outpatient case histories patients with acute bronchitis analyzed and special questionnaire with following questions were elaborated:
300 hospital case histories patients after surgical operations were chosen, randomized, in 2000 year and appraisal was hold. Case history analyses were based on questionnaire which has following questions
Practice antibiotic use in surgical department of state and private hospitals
Antibiotic expenditure decreased on 38,2%
To inculcate program “For prudent use of antibiotics”by means of local antibiotic resistance advisory center creation with independent laboratory foundation (necessary lab equipment and training for lab staff), including following elements: