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Contents (click topic) - PowerPoint PPT Presentation

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Contents (click topic) Employment numbers (life sciences) Health sector activities Types of work environments Research Production Quality Assurance / Control Health companies Health research Chemical and Bioscience Technology Employment Life sciences sector: ~ 4,200 employees

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Contents (click topic)

  • Employment numbers (life sciences)

  • Health sector activities

  • Types of work environments

    • Research

    • Production

    • Quality Assurance / Control

  • Health companies

  • Health research

  • Chemical and Bioscience Technology

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    • Life sciences sector: ~ 4,200 employees

    • 41 companies (17 agri-food, 22 biomedical, 2 environmental)

    • 2300 are in 5 companies (Cangene, Biovail, Apotex, Monsanto & VitaHealth)

    • 30 research and development establishments employ 1900 people

    • There are 23 service firms that support the life sciences industries.

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    Life Science Activities

    • Pharmaceutical research & production

    • Infectious diseases

    • Cardiovascular diseases

    • Cancer / oncology / child health

    • Non-invasive biodiagnostics

    • Molecular biology, Mapping & Gene Cloning

    • Proteomics & Bioinformatics

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    Life Science Activities

    • Bacterial Fermentation & Metabolic Engineering

    • Marker-assisted Gene Selection

    • Proteomics

    • Level 3 & 4 Bio-containment

    • Biological Mass Spectrometry

    • Role of nutrition in health

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    Work Environment

    Three Main Areas:

    • R&D – Research and Development

    • Production

    • QA/QC – Quality Assurance / Quality Control

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    Research Team

    • Works in a laboratory environment

    • Find product / idea with value

    • Characterize: composition, potency, etc.

    • Establish product specifications

    • Develop analytical / manufacture methods

    • Microbiological considerations

    • Raw materials & equipment specifications

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    Research Jobs

    • Scientist

    • Research Scientist

    • Research Associate

    • Research Technician

    • Laboratory Technician

    • Laboratory Scientist

    • Media Preparation Technician

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    Production Team

    • Works in a Production (GMP) facility

    • Makes the product – biochemical, etc.

    • Work with large volumes / equipment

    • Routine operation, cleaning, calibration and maintenance of equipment

    • Monitoring and control

    • Follow SOP (standard operating procedure)

    • Complete forms, labels, log-books (GMP)

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    Production Jobs

    • Manufacturing Operator

    • Manufacturing Technician

    • Manufacturing Supervisor

    • Production Technician

    • Pilot Plant Operator

    • Pilot Plant Technician

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    QA / QC Team

    • Works in office, lab and inspects facility

    • Monitor equipment, facilities, personnel, product

    • Review all production procedures

    • Ensures document / record accuracy

    • Test samples of product and raw materials

    • Compare results to established standards

    • Approve product release

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    QC / QA Jobs

    • Quality Assurance Technician

    • Quality Control Technician

    • Assay Analyst

    • Documentation Specialist

    • Compliance Specialist

    • Internal Auditor

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    Work Environment

    Life Sciences = Regulated Industries

    • Strict controls for materials affecting human health

    • Facilities have to meet exact requirements

    • Methods have to be inspected and approved (Health Canada, FDA, etc.)

    • People have to trained, tested and authorized to participate

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    Work Environment

    Academic / Gov. Research

    • University or Research Organization lab

    • Investigate fundamental problems in biology / chemistry (etc.)

    • “Product” is knowledge or information

    • Research may have to be validated following GLP / ISO

    • Can require degree(s)

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    Work Environment

    R&D Laboratories in Industry

    • Work in-house laboratory (small / large)

    • Investigate with intent of a commercial product, conduct scale-up / pilot plant

    • Focused, aggressive, highly effective

    • Work conducting following recognized protocols: ISO, GLP, etc.

    • Require diploma / degree

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    Work Environment

    Production Facilities

    • Warehouse-scale manufacturing operations

    • May be highly sanitary

    • May be noisy and damp

    • Can be simple job or highly complex

    • Entry from college / high school

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    Work Environment

    Testing Labs (QA, Microbiol, Clinical)

    • Independent or governmental labs

    • Perform tests on samples / devices

    • May be highly routine

    • May be occasionally variable

    • Facility is often certified GLP / ISO

    • Diploma / degree required

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    Health Companies

    Apotex Fermentation Inc.

    • AFI uses fermentation-based technologies for the production of Active Pharmaceutical Ingredients (APIs).

    • The Winnipeg facility is the largest fermentation-based GMP facility in Canada.

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    Health Companies

    Biovail Corporation

    • Formulation, clinical testing, & manufacturing of pharmaceutical products.

    • Biovail has operations in the US and Canada, and a research facility in Ireland.

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    Health Companies

    Medicure Inc.

    • Development of drugs for cardiovascular diseases and stroke.

    • The company's lead product, MC-1, reduces ischemic injury caused by restrictions in blood flow.

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    Infectious Diseases

    Canadian Science Centre for Human and Animal Health (CSCHAH)

    • A leading research location for infectious disease

    • Study human pathogens & zoonotic diseases, prion diseases, influenza virus, enterics, STDs, hepatitis, tuberculosis, genomics, antimicrobial resistance, & foreign animal diseases.

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    Infectious Diseases

    Canadian Science Centre for Human and Animal Health

    • The laboratory is the first and only global centre with level-4 bio-containment capabilities for the study of both human and animal diseases.

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    Institute of Cardiovascular Sciences

    • Involved in drug discoveries for the treatment of heart failure, ischemic heart disease, and diabetes.

    • Located at the St. Boniface General Hospital Research Centre

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    National Centre for Agri-food Research Within St. Boniface General Hospital Research Centre

    • Studies health-related benefits of natural health products

    • Evaluates health benefits, medical side effects, & athletic performance through research and clinical trials.

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    Clinical Trials

    I.H. Asper Clinical Research Institute

    • Links basic medical research programs at the St. Boniface General Hospital Research Centre with patient care.

    • Conducts Phase I and Phase II clinical trials on cutting edge pharmaceuticals for heart disease & stroke.

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    Medical Diagnostics

    Institute for Biodiagnostics (IBD)

    • The National Research Council's IBD investigates instrumentation and methods for noninvasive diagnosis of serious health conditions (cancer, arthritis, heart disease, neurological conditions, and osteoporosis).

    • Has the largest concentration of MRIs and NMRs for R&D purposes in Canada.

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    Child Health

    Manitoba Institute of Child Health

    • Dedicated to pediatric research

    • Has expertise in developmental pharmacology, respirology, genetics, and toxicology.

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    CancerCare Manitoba

    • A key R&D facility (HSC) involved with the prevention, care, and research of cancer

    • Recently constructed a $3 million breast cancer research facility (HSC)

    • Also involved with Radiation Protection consultations and measurement services.

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    Manitoba Institute of Cell Biology

    • Studies the molecular origins of cancer and the role of signal transduction pathways in regulating cell proliferation.

    • Also involved in developing markers of risk of developing invasive breast cancer

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    Genomic Centre for Cancer Research and Diagnosis (GCCRD)

    • Conducts research in genomic instability and mechanisms of neoplasia (formation of new tissue).

    • GCCRD is part of the Manitoba Institute of Cell Biology (MICB), CancerCare Manitoba, and the University of Manitoba.

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    Mammalian Functional Genomics Centre

    • Creates diverse human disease models in mice, for rapid assessment of gene function.

    • Created a library of mouse embryonic stem cells, each with a defined mutation in a cellular gene to help disease modeling

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    Manitoba Centre for Proteomics

    • Analyzes human inflammatory diseases using proteomic approaches and identifies biomarkers for these diseases.

    • The Centre is partnered with Applied Biosystems, Ciphergen Biosystems, and Chemicon International Corp.

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    Biomedical Proteomics Program, University of Manitoba

    • The Biomedical Proteomics Program seeks to connect basic biological, agricultural and biomedical scientists with those scientists developing instrumentation and analytical software.

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    • 32,000 students, 110-plus programs

    • Applied Biopharmaceutical Processing

    • Applied Biology

    • Applied Chemistry

    • Applied Pharmaceutics

    • Chemical and Biosciences Tech Co-op

    • Environmental Protection Technology

    • Medical Laboratory Sciences

    • Medical Radiologic Technology

    • MRI and Spectroscopy

    • QA/QC in Pharmaceutical Industry

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    Chemical and Biosciences Technology

    • 2-year applied program at RRC

    • Features:

      • Co-op job placement

      • Exceptional laboratory training

      • Provides skills employers want

      • Enormous range of grad opportunities

  • Joint 4-year degree program with UW

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    Additional Resources

    • Bioscience Websites - David Blicq / RRC

      • Science Job postings

      • Manitoba Bioscience news

      • Course summaries and lab manuals

      • Resumé and Cover letters

      • On-line courses (viewable content)

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    Additional Resources

    • Other Content:

      • Study skills for science

      • Employer-requested skill-sets

      • Interview tips

      • Lab documentation GLP / ISO

      • Student pages

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    Manitoba Science

    Opportunity & Innovation