Comprehensive Guide to Neuroendocrine Tumours (NETs)

1. Comprehensive Guide to Neuroendocrine Tumours (NETs) Introduction: What Are Neuroendocrine Tumours? Neuroendocrine Tumours (NETs) are rare types of cancers that develop from neuroendocrine cells, which possess both nerve-like and hormone-producing functions. These tumours may occur anywhere in the body but are most commonly found in the intestines, pancreas, stomach, and lungs. NETs vary in behaviour — some are slow- growing, while others can be aggressive. They may release hormones that cause distinct symptoms or remain “silent” for years. Thanks to the progress in modern medicine and diagnostic imaging, early detection and effective treatment are now possible. Dr. Sachin Arora, a renowned Colorectal Cancer Surgeon in Dehradun and Surgical Gastroenterologist, specializes in the diagnosis and management of neuroendocrine and gastrointestinal tumours. His expertise in laparoscopic and minimally invasive surgery has helped numerous patients achieve better recovery and long-term health.

2. Common Symptoms of Neuroendocrine Tumours Neuroendocrine tumours can present with a wide range of symptoms, depending on their location and hormone activity. Some patients experience noticeable signs, while others may remain asymptomatic until the disease progresses. Key Symptoms Include: Abdominal Pain: Persistent or intermittent discomfort in the abdominal region. Diarrhea or Digestive Issues: Frequent diarrhea, bloating, or changes in bowel movement patterns. Flushing of the Skin: Sudden redness or warmth of the face and neck caused by excess hormone release. Unexplained Weight Loss: Gradual weight reduction without any intentional changes in diet or exercise. Hormonal Changes: Fatigue, weakness, or mood swings caused by hormonal imbalance. Since these symptoms often overlap with other gastrointestinal conditions, accurate medical evaluation by a qualified Gastroenterologist or Colorectal Cancer Surgeon in Dehradun is essential for proper diagnosis.

3. Diagnosis and Evaluation Timely diagnosis plays a crucial role in successful treatment of NETs. Multiple diagnostic tools are used to detect tumour presence, size, and spread. Diagnostic Procedures Include: Imaging Tests: Advanced imaging such as CT scan, MRI, and PET scan helps identify the tumour’s exact location and stage. Biochemical Tests: Blood and urine tests to detect abnormal hormone levels like serotonin or chromogranin A. Endoscopy and Colonoscopy: Endoscopic procedures visualize the digestive tract and allow biopsy collection for analysis. Histopathology: Examination of biopsy tissue under a microscope confirms the tumour type and aggressiveness. Dr. Sachin Arora adopts a multidisciplinary diagnostic approach—combining the expertise of gastroenterologists, oncologists, and pathologists—to provide accurate and comprehensive diagnosis for his patients.

4. Treatment Options for Neuroendocrine Tumours Treatment varies based on tumour location, size, grade, and whether it has spread to other organs. The goal is to remove the tumour, control hormone production, and prevent recurrence. Laparoscopic Surgery (Minimally Invasive Removal) Surgery is the most effective treatment for localized NETs. As a highly experienced Laparoscopic and Colorectal Cancer Surgeon in Dehradun, Dr. Sachin Arora performs precise tumour removals using minimally invasive techniques, ensuring: Faster recovery Less pain and scarring Shorter hospital stay Quicker return to normal activities Targeted Therapy and Chemotherapy For advanced or metastatic cases, targeted therapy and chemotherapy are effective in slowing tumour growth and reducing symptoms. Targeted drugs act on specific cellular pathways, minimizing side effects compared to traditional chemotherapy. Hormone-Controlling Medication In hormone-secreting NETs, medications like somatostatin analogues (octreotide, lanreotide) are prescribed to manage hormone-related symptoms such as flushing and diarrhea. Regular Follow-Up and Imaging Long-term surveillance is critical. Regular check-ups with imaging and blood tests help detect any recurrence early and maintain overall health.

5. The Importance of Early Detection Because NETs can remain hidden for years, early diagnosis significantly increases treatment success. Recognizing symptoms such as chronic diarrhea, abdominal discomfort, or unexplained weight loss can lead to early medical intervention. Being a trusted Colorectal Cancer Surgeon in Dehradun, Dr. Sachin Arora emphasizes preventive care and early screening, particularly for individuals with a family history of gastrointestinal or endocrine disorders. Contact Information : - Addresh : Sanjay Medicos, Sector 2, Maharani Bagh Ln, Ballupur Chowk, Ashirwad Enclave, Mohit Nagar, Dehradun, Uttarakhand 248001 Mobile : +917505209117 Conclusion Neuroendocrine Tumours (NETs) may be rare, but with awareness, timely diagnosis, and advanced surgical techniques, they can be effectively managed. Under the expert care of Dr. Sachin Arora, a leading Colorectal Cancer Surgeon in Dehradun, patients receive world-class treatment with personalized care and attention.