Bizarre Biochemistry. Science Lecture Series October 6, 1999 University of San Diego. Water - the Elixir of Life. “Whiskey is for drinking; water is for fighting over.” ( Mark Twain ) Life is bizarre in the desert, ocean & Arctic Consider: Camels, gerbils, Dorcas gazelles, kangaroo rats
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Science Lecture Series
October 6, 1999
University of San Diego
Peroxisomes, like lysosomes, contain powerful enzymes that use molecular oxygen and generate peroxide.
Belladonna - literally
by Eberhard von Kitzing of the Max Planck Inst. in Heidelberg
Atropine prevents the channel from opening - thus blocking nerve impulses
But diaphorase in “blue blood” is unable to reduce metHb effectively
Cawein needed a “cure” that was reliable, safe, available and easy to use - he decided to try a common dye:
He injected one patient with 100 mg of methylene blue. Within minutes, the skin was pink!
He gave methylene blue tablets to each blue family, to take each day, because the effects are temporary and methylene blue is excreted in the urine.
One old mountain man confided to Cawein: “Doc, I can see that old blue running out of my skin.”
The reaction of methemoglobin with the colorless, reduced leucomethylene blue returns the hemoglobin to its normal (red) form.
Plant maceration at harvest facilitates coumarin formation from melilotoside. Molds growing in wet storage conditions can convert coumarin to the anticoagulant dicoumarol.
Vitamin K activates carboxylation of glutamate residues in proteins that trigger blood clotting
Vitamin K is oxidized in this activation and must be recycled continuously.
Warfarin/Coumadin blocks this recycling, preventing the formation of normal blood-clotting proteins.
Smooth Muscle Relaxation