Anticancer therapy: Histone Deacetylase Inhibitors. Afsha Rais. Histones are so cool!. In chromatins, DNA is wrapped around proteins of which most are histones. Histones assist in DNA packaging and have a regulatory role.
for HDAC inhibitors is the
treatment of cancer.
Reversible inhibitor of Histone deacetylase
Induce cell cycle arrest at G1, apoptosis, and cellular differentiation
Has some uses as anti-cancer drug