Parkinson s Disease

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Research. Parkinson's disease is a degenerative sickness of the nervous system. It is caused by a lack of healthy, dopamine producing blood cells, as referred to in the diagram on page 6. It was first described in detail by James Parkinson in his paper written in 1817 called An Essay on the Shaki

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Parkinson s Disease

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1. Parkinsonís Disease By: Kenneth M. Period 6

2. Research Parkinson's disease is a degenerative sickness of the nervous system. It is caused by a lack of healthy, dopamine producing blood cells, as referred to in the diagram on page 6. It was first described in detail by James Parkinson in his paper written in 1817 called ďAn Essay on the Shaking PalsyĒ. However, in AD 175, a physician named Galen wrote a paper named ďShaking PalsyĒ. The French neurologist Jean Martin Charcot named the sickness after james Parkinson 60 years after Parkinsonís paper was published.

3. Research The symptoms are tremors, bradykinesia, akinesia, digestion problems, depression, low blood pressure, temperature sensitivity, leg discomfort, and losing the ability to balance. The tremors are usually localized at first, such as in one toe. It then spreads up the leg. Bradykinesia is slowness of motion. Akinesia is when the muscles become rigid. Digestion problems like low energy and constipation.

4. Research Depression is when you are in a state of sadness. Low blood pressure which can result in fainting and light headedness. Temperature sensitivity can result in excess sweating and hot flashes. Leg discomfort like cramps and sometimes a burning sensation. There is currently no cure, but there are many types of medicine and treatments. One treatment is stem cell treatment. The idea is that you replace the damaged dopamine producing neural cells with stem cells. This has a relatively good success rate at limiting certain symptoms, as referred to in the diagram on slide 7. There are also some types of medication ranging from Levodopa, which basically functions by increasing dopamine levels, to Segeline, which is a MAO-B inhibitor (MAO-B is an enzyme that degrades dopamine).

5. Research Each patient spends approximately 2,500 dollars for medication every year. The average age when you are diagnosed with it is about 60 years.

6. Body Diagram

7. Math Oriented Diagram

8. Interview Q: What is your name? A: Mansour. Q: Who did you know that had Parkinsonís? A: My dad. Q: What symptoms did your father have at first? A: He had pain and tremors in his thumb. Q: When did you find out he had Parkinson's? A: My dad had suspected he had it because his father had had it too. We took him to the doctor and he did some simple test on his elbow. My dad had suspected he had it because his father had had it too.

9. Interview Q: How long after he was diagnosed with Parkinson's did he live? A: Approximately 15 years. Q: How old was he when he passed? A: 85 years old. Q: How did it affect his lifestyle? A: When his medication wore off, he would freeze up and could not move. To make him start walking again, we would make a line out of something like a piece of paper or a ruler in front of his feet.

10. Conclusion I chose to do Parkinson's because my grandfather died of it. I didnít have closure and doing this project definitely helped. The most interesting thing that I learned by doing this project was that the older you are when you get Parkinson's, the slower it progresses. For example, Michael J. Fox was diagnosed at 30 with Parkinson's and the symptoms progressed quickly while my grandfatherís symptoms took about 13 years to become serious.

11. Conclusion The most important source of information I used was a website called Parkinsonís.org. I would still like to know whether it is truly hereditary. I have read mixed opinions on this. I think that the strengths of this report are the interview and the diagrams. I also think that the weakness of the report is the conclusion.

12. Bibliography (1)Web. 12 Mar 2010. <http://www.wnho.net/aspdiagram7.gif>. (2)"Parkinson's Disease." emedicinehealth n. pag. Web. 12 Mar 2010. <http://www.emedicinehealth.com/parkinson_disease/article_em.htm>. (3)"Parkinsons: A Disease Of Aging." About.com: Senior health n. pag. Web. 12 Mar 2010. <http://seniorhealth.about.com/library/weekly/aa012300a.htm>. (4)"Results of our stem cell treatments." Xell-Center. N.p., n.d. Web. 12 Mar 2010. <http://www.xcell-center.com/treatments/results.aspx>. (5)"Parkinson's Disease." Wikipedia. N.p., n.d. Web. 12 Mar 2010. <http://en.wikipedia.org/wiki/Parkinson%27s_disease>. (6) "Parkinson's disease information." Parkinson's.org. N.p., n.d. Web. 12 Mar 2010. <http://www.parkinsons.org/index.html>.

13. Bibliography (7)Mansour M. (8)The book ďParkinsonís Disease: The complete guide for patients and caregivers by: Abraham N. Lieberman, M.D. and Frank L. Williams

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