Epidemiology of maternal and neonatal mortality in malawi
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Epidemiology of Maternal and Neonatal Mortality in Malawi. Dr. Chisale Mhango FRCOG. NPC Training in MNH. MATERNAL MORTALITY IN LOW RESOURCE COUNTRIES: How to accelerated reduction. Objectives: Understand the issues relating to MMR Review Global and Local Progress on Reduction of MMR

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Epidemiology of maternal and neonatal mortality in malawi

Epidemiology of Maternal and Neonatal Mortality in Malawi

Dr. Chisale Mhango FRCOG

NPC Training in MNH


Maternal mortality in low resource countries how to accelerated reduction
MATERNAL MORTALITY IN LOW RESOURCE COUNTRIES: How to accelerated reduction

Objectives:

  • Understand the issues relating to MMR

  • Review Global and Local Progress on Reduction of MMR

    • Key article from The Lancet

  • Discuss effective strategies


Outline of presentation
Outline of presentation accelerated reduction

  • Definitions of terms

  • Global and Local Trends in MMR and NNM

  • Causes of maternal and neonatal mortality

  • Current data on place of delivery in Malawi

  • Coverage for Skilled Birth Attendants in Malawi

  • Rationale for new roles for TBAs

NPC Training in MNH


Definitions
Definitions accelerated reduction

Statistical measurements..

Alternative definition of MD in ICD-10 (1992)


Definitions cont
Definitions cont… accelerated reduction

Definitions and Statistical measurements..


Methods of defining maternal mortality
Methods of defining accelerated reductionMaternal Mortality


Millennium development goal 5 improve maternal health
Millennium Development Goal 5: Improve Maternal Health accelerated reduction

  • Target 5.A:

    • Reduce by 3/4, between 1990 and 2015, the maternal mortality ratio

  • Indicators:

    • Maternal mortality ratio

    • Proportion of births attended by skilled health personnel

  • Target 5.B:

    • Achieve, by 2015, universal access to reproductive health

  • Indicators:

    • Contraceptive prevalence rate

    • Adolescent birth rate

    • Antenatal care coverage

    • Unmet need for family planning


Millennium development goal 4 reduce child mortality
Millennium Development Goal accelerated reduction4: Reduce Child Mortality

  • Target 4:

    • Reduce by 2/3, between 1990 and 2015, the child mortality rate

  • Indicators:

    • Under-five mortality rate

    • Infant mortality rate

    • Proportion of 1 year-old children immunized against measles


The lancet article
The Lancet accelerated reductionArticle

Maternal mortality for 181 countries, 1980–2008:a systematic analysis of progress towards Millennium Development Goal 5

Margaret C Hogan, Kyle J Foreman, Mohsen Naghavi, Stephanie Y Ahn, Mengru Wang, Susanna M Makela, Alan D Lopez, Rafael Lozano, Christopher J L Murray

Volume 375 May 8, 2010, pp. 1609-1623.


Map of priority countries
Map of Priority Countries accelerated reduction


Global situation
Global Situation accelerated reduction

180-210 million pregnancies annually

80 million unwanted pregnancies

50 million induced abortions

20 million unsafe abortions

68,000 deaths from unsafe abortion

20 million women suffer from maternal morbidity

Estimated 350,000 to 450,000 maternal deaths

3million babies are born dead

Almost 10 million children under age of 5 die

Of which 3 million newborns die within the first week

500,000 infants are infected with HIV


Every single minute
Every Single accelerated reductionminute…

…1 woman dies

…380 women become pregnant

…190 women face an unplanned

or unwanted pregnancy

…110 women experience

pregnancy-related complications

…40 women have an unsafe abortion


Mm who estimates
MM WHO estimates accelerated reduction


Mm who estimates1
MM WHO… Estimates accelerated reduction


Maternal mortality the latest data
Maternal Mortality: accelerated reductionThe latest data

“These numbers should now act as a catalyst, not a brake, for accelerated action on MDG-5, including scaled-up resource commitments. Investment incontrovertibly saves the lives of women during pregnancy.” Richard Horton

Source: Hogan MC et al. Maternal mortality for 181 countries, 1980-2008: a systematic analysis of progress towards Millennium Development Goal 5. The Lancet 2010: published online April 12. doi:10.1016/S0140-6736(10)60518-1.

For the first time, new data indicate that we are seeing real progress in reducing maternal mortality worldwide.

A new study published in The Lancet in May 2010 revealed that the number of women dying from pregnancy-related causes has declined from 526,300 in 1980 to 342,900 in 2008.

The finding contradict previous research which showed very little change in reducing maternal mortality, and represent a powerful opportunity to show that investments to reduce maternal mortality actually work.


Current situation
Current Situation accelerated reduction

6 Countries Account for 50%

of Maternal Mortality

- India - Afghanistan

- Nigeria - Ethiopia

- Pakistan - Democratic Republic of the Congo


Countdown to 2015
Countdown to 2015 accelerated reduction

NPC Training in MNH


Trends in maternal mortality in malawi un estimates with extrapolation to 2015
Trends in Maternal Mortality in Malawi: accelerated reductionUN Estimates with extrapolation to 2015

NPC Training in MNH


Trends in under 5 mortality rate top line and infant mortality rate lower line in malawi
Trends in Under-5 Mortality Rate (top line) and Infant Mortality Rate (lower line) in Malawi


Neonatal mortality rate in malawi
Neonatal Mortality Rate in Malawi Mortality Rate (lower line) in Malawi

NPC Training in MNH


Causes of maternal mortality
Causes of Maternal Mortality Mortality Rate (lower line) in Malawi


Main direct causes of maternal deaths in malawi
Main direct causes of maternal deaths Mortality Rate (lower line) in Malawiin Malawi

  • Haemorrhage after childbirth (27%)

  • Sepsis after childbirth (23%)

  • Hypertension of Pregnancy (17%)

  • Complications of unsafe abortion (16%)

    ALL THESE CONDITIONS ARE COMMONEST WITH CHILDBIRTH OR ABORTION OUTSIDE HEALTH FACILITIES

Source: MDHS2010

NPC Training in MNH


Main causes of neonatal deaths
Main causes of neonatal deaths Mortality Rate (lower line) in Malawi

  • Birth asphyxia

    • lack of resuscitation skills at birth

  • Low birth weight

    • Prematurity leading to

      • Cold injury

      • RDS

    • HIV

  • Severe infections

    • Home births

NPC Training in MNH


Time of death
Time of Death Mortality Rate (lower line) in Malawi


Key strategies to reduce maternal mortality
Key strategies Mortality Rate (lower line) in Malawito reduce maternal mortality


What factors are driving maternal mortality in malawi
What factors are driving Mortality Rate (lower line) in Malawimaternal mortality in Malawi?

Not only medical issues, but also a social, economic, political and human rights issues

  • Poverty

    • No food security

  • Low female literacy rates

    • Cultural factors

  • High fertility rate

  • Poor functioning health infrastructure

    • Contraceptive services

    • Insufficient focus on quality of care

    • Inadequate number of skilled health workers.

    • Physical infrastructure

    • Basic tools of the trade

  • Slow adoption of evidence based policy

“I am going to fetch a baby. The journey is dangerous and I may not return …”


Maternal mortality the link to family planning
Maternal Mortality: Mortality Rate (lower line) in MalawiThe Link to Family Planning

3.70

3.26

2.56

The Lancet study data indicate that the global decline in fertilityis a key contributing factor to the decline in maternal mortality.

Societies in which the total fertility rate has decreased are also those in which maternal mortality has decreased.

Global decline in total fertility rate (TFR)

I__________________I_________________I

19801990 2008


Skilled attendance at birth saves mothers and babies
Skilled attendance at birth Mortality Rate (lower line) in Malawisaves mothers and babies

Skilled attendance at childbirth

is the most effective intervention


Access to skilled birth attendants
Access to skilled birth attendants Mortality Rate (lower line) in Malawi

About 35 % of pregnant women in developing countries have no access to, or contact with, health personnel before delivery, and only 57 % give birth with a skilled attendant present.


Access to emergency obstetric care
Access to emergency obstetric care Mortality Rate (lower line) in Malawi

EmOC

  • 42 % of all pregnancies everywhere experience a complication. In 15 % of all pregnancies, the complications arelife-threatening.

  • 61 % of maternal deaths occur just before, during, or just after delivery, often from complications that cannot be predicted and are difficult to prevent

  • Therefore… it is critical that every woman have access to emergency obstetric care


Why women do not access health services
Why Women Do Not Access Mortality Rate (lower line) in MalawiHealth Services?

  • Distance from health services

  • Lack of transportation

  • Cost

  • Multiple demands on women’s time

  • Lack of decision-making power within

    the family

  • Attitude of health care providers

  • Limited access to education

  • Inadequate health care services

  • Discriminatory or inadequate laws or health care policies

  • Culture

  • Community


Reasons for decrease of maternal mortality
Reasons for decrease Mortality Rate (lower line) in Malawiof maternal mortality

Global decrease in Total Fertility Rate (TFR)

Increase of income in low-income countries

Increase in maternal education

Increase in skilled birth attendants from approximately 25% to 45–55%


1 what interventions work
1. What Interventions Work? Mortality Rate (lower line) in Malawi


2 what interventions work
2. What Interventions Work? Mortality Rate (lower line) in Malawi


3 what interventions work
3. What Mortality Rate (lower line) in MalawiInterventions Work?

  • Access to quality care for pregnancy and childbirth

    • - Antenatal care

    • - Skilled attendance at birth, including emergency obstetric and neonatal care

    • - Immediate postnatal care for mothers and newborns

  • Access to family planning

    • - Counseling

    • - Services

    • - Modern contraception

  • Access to safe abortion (when legal)

childbirth

  • - Antenatal care

  • - Skilled attendance at birth, including emergency obstetric and neonatal care

  • - Immediate postnatal care for mothers and newborns

  • Access to family planning

    • - Counseling

    • - Services

    • - Modern contraception

  • Access to safe abortion (when legal)

    • Strong health systems

      • - Scaling-up critical health interventions

      • - Training health care professionals

      • - Training of mid-wives

    • Accelerated access to life-saving, interventions, medicines and vaccines

      • - Vaccines to target pneumonia, tetanus, and diarrhea

      • - Prevention, screening and treatment of HIV and STIs

      • - Treatment and prevention of malaria, pneumonia and diarrhea


    Coverage failures across Mortality Rate (lower line) in Malawi

    the continuum of care GLOBALLY

    • For some interventions:

    • Family planning

    • Exclusive breastfeeding

    • Clinical care for newborn and child illnesses

    • In some

    • countries:

    • Wide gaps in coverage across countries

    Coverage estimates for interventions across the continuum of care in the 68 priority countries (2000-2006).

    Vertical bars indicate the range in coverage across countries.


    Place of delivery in malawi
    Place of Delivery in Malawi Mortality Rate (lower line) in Malawi

    URBAN

    RURAL

    71% in health facilities

    70% had skilled attendance at birth

    For all Malawi, 73% women had skilled attendance at childbirth

    • 84% in health facilities

      • 85% had skilled attendance at birth

    • For all Malawi 72% delivered in health facilities

    • 98% women with tertiary education had skilled attendance at childbirth compared to 63% women without education.

    NPC Training in MNH

    Source: MDHS 2010


    Which women and n ewborns were dying the most in malawi
    Which women and Mortality Rate (lower line) in Malawinewborns were dying the most in Malawi?

    Mothers

    Neonates

    Babies born without skilled attendant present at birth.

    Suffered the most from birth asphyxia, cold injury and infection, especially if they were under weight or premature

    • Women who delivered or procured abortion outside the health facilities, especially when they developed, PPH, PIH and sepsis

      • Women who developed these complications while in health facility, had treatment initiated earlier and were less likely to die.

    NPC Training in MNH


    Rationale for change of tba roles
    Rationale for Change of TBA roles Mortality Rate (lower line) in Malawi

    • International WHO and local studies revealed that investment in TBAs did not contribute significantly to reduction of maternal and neonatal deaths

    • The option of TBA births prevented the scale up of skilled attendance at child births

      • As soon as the TBA option was removed in Malawi, health facility births soared, distance of health facility had been overestimated

    NPC Training in MNH


    Trends in skilled attendance at birth in malawi
    Trends in Skilled Attendance at Birth in Malawi Mortality Rate (lower line) in Malawi

    NPC Training in MNH


    There is no better time Mortality Rate (lower line) in Malawito reduce maternal and child death in Malawi - Commited leadership critical


    References reading
    References/reading Mortality Rate (lower line) in Malawi

    B-Lynch C, Keith LG, Lalonde AB, Karoshi M. A Textbook of Post Partum Hemorrhage: A comprehensive guide to evaluation, management and surgical intervention. Sapiens Publishing, 2006.

    Chowdhury ME, Botlero R, Koblinsky M, Saha SK, Dieltiens G, Ronsmans C. Determinants of reduction in maternal mortality in Matlab, Bangladesh: a 30-year cohort study. Lancet 2007; 370: 1320–28.

    Countdown Coverage Writing Group, on behalf of the Countdown to 2015 Core Group. Countdown to 2015 for maternal, newborn, and child survival: the 2008 report on tracking coverage of interventions. Lancet 2008; 371: 1247–58

    Deneux-Tharaux C, Berg C, Bouvier-Colle MH, et al. Underreporting of pregnancy-related mortality in the United States and Europe. ObstetGynecol2005; 106: 684–92.

    Fortney JA, Leong M. Saving Mother’s Lives: Programs that work. ClinObstetGynecol2009; 52: 224.

    Graham WJ, Ahmed S, Stanton C, Abou-Zahr CL, Campbell OM. Measuring maternal mortality: an overview of opportunities and options for developing countries. BMC Med 2008; 6: 12.

    Hogan MC, Foreman KJ, Naghavi M, Ahn SY, Wang M, Makela SM, Lopez AD, Lozano R,

    Landagan OZ, Barrios EB. An estimation procedure for a spatial-temporal model. Stat ProbabLett2007; 77: 401–06.

    The Millennium Development Goals Report 2008. New York: United Nations, 2008.

    Murray CJL, et al. Maternal mortality for 181 countries, 1980–2008: a systematic analysis of progress towards Millennium Development Goal 5. Lancet 2010,375: 1609-1623

    Ronsmans C, Graham WJ, on behalf of The Lancet Maternal Survival Series steering group. Maternal mortality: who, when,where, and why. Lancet 2006; 368: 1189–200.

    WHO. International statistical classification of diseases and related health problems, tenth revision instruction manual (2 edn). Geneva: World Health Organization, 2004.

    WHO, PMNCH. Joint Action Plan for Women’s and Children’s health. Geneva: World Health Organization, Partnership for Maternal, Newborn and Child Health, 2010 Draft.

    WHO, UNICEF. Countdown to 2015 Decade Report (2000-2010): Taking stock of maternal, newborn and child survival. Geneva: World Health Organization and UNICEF, 2010.

    WHO, UNICEF, UNFPA, World Bank. Maternal mortality in 2005: estimates developed by WHO, UNICEF, UNFPA and the World Bank. Geneva: World Health Organization. 2007.

    WHO. WHO Mortality Database. Geneva: World Health Organization, 2010. http://www.who.int/whosis/mort/download/en/index.html (accessed March 23, 2010).


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