1 / 23

Total synthesis of (-)Quinocarcin

Total synthesis of (-)Quinocarcin. Mounuo Cheng 20091115. DX-52-1 R=CN Quinocarcinol R=H. Quinocarcin. terazomine. quinocarcinamide. quinocarcinamide. Jieping Zhu Jacs 2008,130, 7148-7152. Jieping Zhu Jacs 2008,130, 7148-7152. Catalytic enantioselective enolate alkylation under PTC.

tivona
Download Presentation

Total synthesis of (-)Quinocarcin

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Total synthesis of (-)Quinocarcin Mounuo Cheng 20091115

  2. DX-52-1 R=CN Quinocarcinol R=H Quinocarcin terazomine quinocarcinamide

  3. quinocarcinamide Jieping Zhu Jacs 2008,130, 7148-7152

  4. Jieping Zhu Jacs 2008,130, 7148-7152

  5. Catalytic enantioselective enolate alkylation under PTC M. J. O Donnell Jacs, 1989, 111, 2353-2355 E. J. Corey Jacs, 1997, 119, 12414-12415

  6. Jieping Zhu Jacs 2008,130, 7148-7152

  7. Pictet-spengler

  8. HOAt HATU Jieping Zhu Jacs 2008,130, 7148-7152

  9. Jieping Zhu Jacs 2008,130, 7148-7152

  10. Jieping Zhu Jacs 2008,130, 7148-7152

  11. Philip Garner Jacs 1993,115, 10742-10753

  12. Triton B Philip Garner Jacs 1993,115, 10742-10753

  13. Philip Garner Jacs 1993,115, 10742-10753

  14. Philip Garner Jacs 1993,115, 10742-10753

  15. Philip Garner Jacs 1993,115, 10742-10753

  16. Brian M. Stoltz Jacs 2008,130, 17270-17271

  17. Ortheogonal synthesis of indolines and isoquinolines cia aryne annulation R1 = OtBu R2 = Ar, alkyl, …

  18. Brian M. Stoltz Jacs 2008,130, 17270-17271 NMM TBAT

  19. Brian M. Stoltz Jacs 2008,130, 17270-17271

  20. Fmoc Andrew G. Myers Jacs 2005,127, 16796-16797

  21. Thank for your attention

More Related