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GalliPro Bacillus based probiotic

GalliPro Bacillus based probiotic. Bacillus spore ideal as probiotic for chicken. GalliPro Comprise live Bacillus spore – natural encapsulated bacteria Survive feed pelleting process and in feed storage Has compatibility with all EU approved coccidiostats

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GalliPro Bacillus based probiotic

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  1. GalliProBacillus based probiotic

  2. Bacillus spore ideal as probiotic for chicken • GalliPro • Comprise live Bacillus spore – natural encapsulated bacteria • Survive feed pelleting process and in feed storage • Has compatibility with all EU approved coccidiostats • Transform from spores to active cells in the intestine of chicken • Reduce FCR • Increase weight gain • Increase nutrient utilization by excretion of enzymes • Improves intestinal health and absorption capacity • Modulate intestinal microflora resulting in more Lactic Acid Bacteria • Reduce Salmonella and Campylobacter

  3. Bacillus sp. • Definition of Bacillus • Gram positive organisms • Spore formers • Bacillus is facultative aerobe but at present of nitrate/nitrite it can grow anaerobic • Bacillus is found in soil and marine sediments • Bacillus as probiotic is in the form of Bacillus spore – a dormant resistant stage that can transform to a vegetative cells • Bacillus spores are • pH stable at pH 2-3 • Trypsin stable • Thermo-tolerant • In-Feed stable

  4. Bacillus spores the ideal probiotic for chicken? Pelletizing study on selected probiotic strains on the market • Pelletizing at 85C 30 sec.: External facility, Bioteknologisk Institut, Denmark • Microbiological analysis: External lab, LUFA –ITL-GmbH, Germany Result: Viable cell count in average CFU/g feed and the recover of viable

  5. Bacillus spores the ideal probiotic for chicken? • Bacillus spore extremely resistant – easy to apply into feed • Bacillus spore germination occurred rapidly in the GI tracts of chicken (Cartman et al 2008) • Vegetative cells can be detected throughout the GI tract of chicks (Cartman et al 2008) • Feeding Bacillus subtilis to chicken resulted in greater growth performance and intestinal histologies such as increasing villus height. Villus tip showed no damage (Samanya & Yamauchi 2002) • Indicating improved nutrient utilization capacity

  6. Bacillus spores the ideal probiotic for chicken? Feeding GalliPro • More diverse and complex bacteria composition in the gut • Expectedly provides more robust microbiota less susceptible towards diseases and infections (Lan et al 2005) • High numbers of Lactic Acid Bacteria • Considered beneficial due to their putative health properties – protect against pathogens colonization and immune stimulation of the host • Lactobacillus salivarius • Strong probiotic characteristics reducing Salmonella and E. coli (Pascual et al 1999, Brashears et al 2003) • Lactobacillus paracasei • Stimulate the immune system of the host (Herich et al 2002, Morelli et al 2003)

  7. GalliPro reduces the level of Campylobacter in broiler chickens • The result shows a significant reduction of Campylobacter by 52% in the GalliPro treated group. • The results on ileal samples showed a 40% reduction of Campylobacter. • Our finding of Campylobacter is accordance with literature. Corry and Atabay (2001) reported the commonly observed level in bird intestinal to be 105 to 107 CFU/g.

  8. GalliPro significantly reduce Salmonella in chicken • Salmonella challenge pen floor study (SPR, US) with and without GalliPro showed a significantly reduction of Salmonella in the GalliPro treated group • All samples were found positive at day 42 in the control group whereas only 43% of the samples in the GalliPro group were positive with regards to Salmonella a b Different letters indication significant difference P< 0.05

  9. Bacillus spores the ideal probiotic for chicken? • GalliPro produceenzymes • Alcalin phosphatase • Esterase • Esterase lipase • Lipase • Leucine amino-peptidase • Valine amino–peptidase • Acid phosphatase • Glucosidase Bacillus shows amylolitic (starch), lipolytic (fat) and proteolytic (protein) activities

  10. Summary of 17 trialsGalliPro vs. Negative Control • Relative efficacy of GalliPro in broiler trials at independent research institutes • Avg. improvement: Final bodyweight +2,8% & FCR -3,8% +2,8% -3,8%

  11. Big increases in in-vivo nutrient utilisation • GalliPro increased in-vivo dry matter, crude protein and gross energy digestibilities, N retention and metabolisable energy. Study 2 at University Federal de Viçosa, Brazil

  12. GalliPro Works! • Increased in-vivo DM, CP & GE digestibilities • Increased weight gain, improved FCR and lower mortality • Canadian & EU Registration • Safe, stable and easy to use • Consistent performance

  13. Bacillus spores the ideal probiotic for chicken? Bacillus subtilis (DSM17299) compatibility with Coccidiostats: • Amprolium/ethopabate • Diclazuril • Halofuginone • Lasalocid sodium • Maduramicin ammonium • Methylbenzoquate/meticlorpindol • Monensin sodium • Narasin • Nicarbazin • Nifursol • Robenidine • Salinomycin sodium • Semduramicin

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