Name ____________________                           BCOR 011 Vayda/Stratton Sept 14, 2005
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C. If the pH of a cytoplasmic compartment falls from 7.0 to 6.0 then: 14) the gloves must fit PowerPoint PPT Presentation


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Name ____________________ BCOR 011 Vayda/Stratton Sept 14, 2005 PRACTICE EXAM QUESTIONS Lectures 1, 2 & 3 (Bonding & Functional Groups, Water, pH & Hydrophobicity, Carbohydrates, Lipids, Nucleic Acids &n Proteins, Cell Tour)

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C. If the pH of a cytoplasmic compartment falls from 7.0 to 6.0 then: 14) the gloves must fit

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C if the ph of a cytoplasmic compartment falls from 7 0 to 6 0 then 14 the gloves must fit

  • Name ____________________ BCOR 011 Vayda/Stratton Sept 14, 2005

  • PRACTICE EXAM QUESTIONS

  • Lectures 1, 2 & 3 (Bonding & Functional Groups, Water, pH & Hydrophobicity, Carbohydrates, Lipids, Nucleic Acids &n Proteins, Cell Tour)

  • NOTE: MEMBRANE STRUCTURE AND FUNCTION WILL BE ON THE EXAM

  • These are “dry-runs” for the Exams you will take. The questions here ARE exam questions from previous years (that’s why the jokes are so out of date). You will see questions similar to these on Sept 23 (with fresher jokes).

  • Section I. MULTIPLE, Multiple Choice.

  • Rarely is there just one right answer in life. These questions are designed to explore the different characteristics of individual things, processes or properties. Practice looking for ALL possible characteristics of an item while you are studying your notes.

  • Indicate all of the answers below that correctly relate to the questions in bold type. Note: there is frequently more than one right answer! Sometimes there IS only one correct choice, other times none of the choices are correct, or all may be correct. Think of this as a type of “true-false” choice for each possible answer to the question. When you fill out the “bubble” answer sheet column 1 will be “true”, column 2 will be ”false”. On the the practice exam

  • below, you have 200 answer choices: so each choice is worth 0.5 pt; that is, if you say it is correct and it is, you get 0.5 pt; if you don’t say it is correct and it is, you lose 0.5 pt, etc. We the actual exam will probably be shorter (have less answer choices, like 150), so each choice will be worth more (like 0.67 pt). You only have 50 min for the 9/23 exam.

A. The structure at right:

1) is a -sheet (beta)

2) is a base pair

3) is a micelle

4) is a starch grain

5) is an polysaccharide

3

B. The tertiary structure of a protein is:

6) the overall 3-D structure of the protein.

7) dictated by interactions of amino acid R-groups with one another.

8) dictated by interactions of the N-terminus with the C-terminus of the polypeptide.

9) influenced by the presence of disulfide bonds.

10) influenced by hydrophobic interactions.

11) the interaction of two or more polypeptide chains to form a protein complex.

12) the interaction of individual amino acids with one another to form a polypeptide.

13) dictated by how the surfaces of secondary structures interact with one another.

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7

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C. If the pH of a cytoplasmic compartment falls from 7.0 to 6.0 then:

14) the gloves must fit

15) the amount of H+ (hydronium) ions has increased

16) the amount of -OH (hydroxide) ions has increased

17) an acid with a pKa of 4.2 will lose its negative charge

18) a base with a pKb of 6.8 will become positively charged

19) phosphate functional groups will become positively charged

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18


C if the ph of a cytoplasmic compartment falls from 7 0 to 6 0 then 14 the gloves must fit

D. Which of the following biologically-important linkages are the result of condensation/dehydration reactions:

20) peptide bonds

21) ester linkages

22) phosphodiester bond

23) James Bond

24) hydrogen bonds

25) Van der Waal’s interactions

26) Glycosidic bonds

20

21

22

26

E. Covalent bonds:

27) are formed when two atoms share electrons.

28) enable atoms to form molecules with stable, precise spatial configurations

29) give the molecule a positive charge at high pH

30) can be purchased through your stockbroker.

27

28

F. Atoms interact to attain chemical stability by:

31) sharing electrons to form covalent bonds

32) sharing the Oval Office

33) “stealing” electrons to complete a stable outer electron shell

34) forming micelles

35) sharing intimate secrets with Linda Tripp

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33

G. Chiral carbons:

36) are found in carbohydrate polymers

37) are found in amino acids

38) are found in polypeptides

39) were found at Rockingham

40) are found in saturated fatty acids

41) are found in water

42) are found in DNA

43) have 4 different functional groups attached to them

44) cannot interact with water

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37

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42

43

H. Amino acids:

45) as monomers, can be expected to be ions at pH 7.0

46) with non-polar “R” groups include alanine, valine and leucine.

47) can be joined in linear polymers to form polypeptides.

48) were allegedly used by Nicole and Faye Resnick

49) with alcohols for “R” groups include threonine and serine

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46

47

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C if the ph of a cytoplasmic compartment falls from 7 0 to 6 0 then 14 the gloves must fit

  • Intracellular membrane-bound organelles:

  • 50) Are typically observed in Prokaryotes

  • 51) Comprise distinct compartments within the cytoplasm

  • 52) Are the cell’s lock boxes

  • 53) Include “mitochondria”

  • 54) are typically observed in Eukaryotes

  • 55) include the “Golgi Apparatus”

  • 56) include the “endoplasmic reticulum”

  • 57) include “ribosomes”

  • 58) include “nuclei” (plural of “nucleus”)

  • 59) contain “phospholipids” in their membranes

  • 60) allow different functions to occur in a cell at the same time

  • 61) allow different microcompartments within the cell to have distinct internal pH’s

  • 62) allow the cell to maximize effective surface area

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  • J. Water has a tendency to :

    • 63) Form hydrogen bonds with polar molecules

    • 64) Form hydrogen bonds with non-polar molecules

    • 65) Form four oxygen bonds with carbon molecules

    • 66) ionize and form the charged species –OH and H+

    • 67) Form hydrogen bonds with hydrocarbon chains (R-CH2-CH2-CH2-CH3)

    • 68) Form hydrogen bonds with amino groups (R-NH2)

    • 69) Bomb Iraq

    • 70) Let the weapons inspectors do their job

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K. A Carbon atom always makes this number of covalent bonds:

71) one

72) two

73) four

74) eight

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L. Eukaryotic cells differ from prokaryotic cells in that eukaryotic cells:

75) are typically much larger than prokaryotic cells

76) contain internal membranes and membrane bound organelles whereas

prokaryotic cells typically do not

77)) store their genetic information in the DNA whereas prokaryotic cells use RNA to store genetic information

78) have nuclei whereas prokaryotic cells do not

79) have viruses whereas prokaryotic cells do not

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C if the ph of a cytoplasmic compartment falls from 7 0 to 6 0 then 14 the gloves must fit

  • Which of the following is a membrane-bound organelle?

  • 80) ribosome

  • 81) nucleus

  • 82) triglyceride

  • 83) microtubule

80

N. A covalent bond between a carbon and a hydrogen atom is considered:

84) nonpolar

85) polar

86) ionic

87) ironic

88) romantic

84

O. A solution with a pH of 5 :

89) has a hydrogen ion concentration of 1x10-9M

90) has a water concentration of 5 M

91) has a hydrogen ion concentration of 0.00001M

92) cannot form hydrogen bonds

91

  • P. A carboxylic acid group with a pKa of 5.5:

    • 93) Will be ionized at pH 7.0

    • 94) Will be uncharged at pH 7.0

    • 95) Will be uncharged at pH 4.0

    • 96) Will be uncharged at pH 8.8

    • 97) Will bear a negative charge in a solution that has 1x10-10 M –OH ions

    • 98) Can form a condensation reaction with an alcohol group to form an ester bond

    • 99) Is hydrophilic

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Q. Which of the following components are found in prokaryotes (bacteria and cyanobacteria)?

100) plasma membrane

102) nucleus

103) endoplasmic reticulum

104) golgi apparatus

105) ribosomes

106) DNA

107) bloody gloves

108) mitochondria

109) chloroplasts

110) lysosomes

111) Bruno Magli shoes

100

105

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C if the ph of a cytoplasmic compartment falls from 7 0 to 6 0 then 14 the gloves must fit

R. Carbohydrate polymers are polar molecules which tend to:

112) be insoluble in water.

113) hydrogen bond with themselves rather than water.

114) form micelles which are great for cleaning greasy dishes.

115) be slimy, gooey or gelatinous when forced to be fully hydrated by water.

116) serve as recognition markers on external surfaces of membrane proteins.

117) hydrolyze peptide bonds.

112

113

115

116

S. Which of the following components are usually found in DNA:

118) phosphatidyl Choline

119) Glutamic acid

120) the preservative EDTA

121) Adenosine monophosphate

122) phosphatidyl Inositol

123) Threonine

124) deoxyRibose

121

124

T. Phospholipids tend to:

125) form aromatic rings.

126) be solids at room temperature if comprised of unsaturated fatty acids.

127) form cholesterol.

128) be hydrolyzed to cholesterol and wax.

129) form bilayers and vesicles.

130) bear a negative charge at pH 7.0.

129

130

U. Which of the following structures represents a monosaccharide?

131) C12H22O11

132)

133)

HO – C = O

|

H – C – OH

|

H – C – OH

|

H

132

134)

V. An alpha helix ( a-helix ) :

135) Is a “primarystructure” that a polypeptide can adopt

136) Is formed when one polar peptide bond hydrogen bonds with another peptide bond further down the chain

137) is held together by disulfide bonds

138) Is the covalent bonding arrangement that holds two polypeptides into a quaternary structure

139) Is a secondary structure of DNA and other polynucleotide chains

136


C if the ph of a cytoplasmic compartment falls from 7 0 to 6 0 then 14 the gloves must fit

W. Which of the following are considered “hydrophobic” aminoacids with “hydrophobic”

R groups

140) glucose144) serine148) palmitic acid

  141) leucine145) valine

  142) phenylalanine 146) glutamine

  143) adenine147) lysine

141

142

145

1.

X. The molecule below :

149) is the L form of an amino acid

150) is likely to be a liquid oil

151) is a pentose

152) is likely to bear a negative (-) charge at pH 7.0

153) is a trisaccharide

154) is comprised of one or more unsaturated fatty acids

155) is hydrophobic

156) was found on Monica Lewinski’s dress

150

154

155

156

Among other things

Note: will never take off for a “joke” answer

Y.The SECONDARY STRUCTURE of DEOXYRIBONUCLEIC ACID (DNA) polymer:

157) Is formed by linking ATP mononucleotides together

158) Is a double-helix of anti-parallel strands

159) Is an alpha (a) helix of two parallel strands

160) Is a beta (b) helix of two anti-parallel strands

161) Is stabilized by precise hydrogen bonding of complementary “bases” trapped in a non-polar microenvironment; A with T, G with C

162) Is driven by the need for hydrophobic bases to stack on top of one another

163) Is driven by the insatiable desire for Bill Clinton to stack… (let’s not go there)

164) Is driven by the political motives of Kenneth Starr

165) Has the negatively (-) charged phosphate groups on the outside, exposed to water

166) is maintained “fluid” by the presence of unsaturated fatty acids in the polymer

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161

162

165


C if the ph of a cytoplasmic compartment falls from 7 0 to 6 0 then 14 the gloves must fit

BB. Which of the following amino acids has a hydrophilic R-group ?

181) isoleucine 182) threonine 183) arginine 184) glutamic acid

Z. The monomers which make up a polypeptide are:

167) held together by phosphodiester bonds

168) chiral

169) nitrogenous bases

170) unsaturated

171) nucleotides

172) amino acids

173) monosaccharides

174) interns

168

172

AA. Cellulose and Amylose (starch):

175) both contain the exact complement of amino acids but arranged in different orders

176) are both polymers of D-glucose but monomers of one are bound together by a1-4 glycosidic linkages whereas the other is bound together by b1-4 glycosidic linkages

177) are both polysaccarides, but one is hydrophobic and the other is hydrophilic

178) are polymers comprised of glucose but have very different 3-D shapes

179) are amphipathic molecules

180) are buffers which can bind ATP

176

178

182

183

184


C if the ph of a cytoplasmic compartment falls from 7 0 to 6 0 then 14 the gloves must fit

  •  CC. Familiarity with the properties of water is important to understand:

  • 185) Why polymers adopt the secondary and tertiary structures they do

  • 186) How soap works

  • 187) What chirality is

  • 188) What a “lock box” is

  • 189) Why we need a tax cut (didn’t Reagan try this already?)

  • 190) Why some hydronium (H+) ions and hydroxide (-OH) ions are always present for reactions in water

  • 191) Why hydrophilic polymers tend to hydrogen bond with themselves rather than water

  • 192) Who this Chad guy is

  • 193) How Chad got pregnant.

  • 194) Why membranes form in water

  • 195) Why carbon atoms can form covalent bonds with 4 other atoms

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194

DD. A molecule that is Chiral has :

196) an unshared pair of electrons

197) a pH of 7

198) hydrophobic character

199) a left-handed and right-handed form

200) at least one carbon with four different functional groups bonded to it

199

200

2. The fluid mosaic model of membranes predicts that:

a) O.J. did it.

b) phospholipids are free to move laterally in membranes.

c) proteins are free to move laterally in membranes.

d) fluids are free to pass through membranes but solid particles cannot.

e) polypeptides are embedded in a sea of phospholipids.

f) polymers of a-D-glucose are soluble in water whereas polymers of b-D-glucose are not.

B

C

E


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