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Brief Cognitive Assessment based on Consensus Standards in the US and Abroad

Brief Cognitive Assessment based on Consensus Standards in the US and Abroad. Dawn Langdon PhD. MS care providers needs. Most interested in receiving consultation on cognition (31.0%) Most interested in CME relating to cognition (40.1%) Highest preference for live conference.

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Brief Cognitive Assessment based on Consensus Standards in the US and Abroad

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  1. Brief Cognitive Assessment based on Consensus Standards in the US and Abroad Dawn Langdon PhD

  2. MS care providers needs • Most interested in receiving consultation on cognition (31.0%) • Most interested in CME relating to cognition (40.1%) • Highest preference for live conference Turner et al., JRRD 2006;43:25-34

  3. MS patients’ information needs • All those questions recommended information about cognition in MS for all patients • And on average to be given earlier than they had received it Heesen et al., ActaNeurol Scand 2006;114:268-272

  4. MSNQ Screening tests BRB SEFCI Brief Batteries MACFIMS Intermediate length Batteries Ad hoc Comprehensive Batteries Assessment of Cognition Routine in the office Routine NP exam. Differential diagnosis Disability questions Rehabilitation programs 4

  5. Cognitive assessment for MS • Requires specialist training • Time-consuming • Not routinely available outside specialist centres • Not comparable across countries

  6. BICAMSBrief International Cognitive Assessment for MS • Identify a brief assessment tool for cognition in MS • can be used by health care professionals who are not cognitive specialists • has international validation • Specify an international validation protocol that can be implemented in any country • Agree guidelines on test-retest timing and clinically significant change BICAMS committee meetings and website are sponsored by Bayer Healthcare

  7. BICAMS committee meetings and website are sponsored by Bayer Healthcare

  8. BICAMSBrief International Cognitive Assessment for MS • Identify a brief assessment tool for cognition in MS • 80 key scientific articles identified • Each article rated by two committee members • Psychometric standards • Reliability • Validity • Sensitivity • Pragmatic standards • International applicability • Ease of administration • Feasibility in the specified context • Acceptability to patients BICAMS committee meetings and website are sponsored by Bayer Healthcare

  9. BICAMSBrief International Cognitive Assessment for MS • No materials required beyond papers, pencil and stopwatch BICAMS committee meetings and website are sponsored by Bayer Healthcare

  10. Benedict et al. Clin Neuropsychol 2002; 16: 381-97

  11. Neuropsychological EvaluationsCalifornia Verbal Learning Test-II (CVLT II) Truck Spinach Giraffe Bookcase Onion Motorcycle Cabinet Zebra Coach Lamp Celery Cow Desk Boat Squirrel Cabbage Benedict et al. Clin Neuropsychol 2002; 16: 381-97

  12. Brief Visuospatial Memory Test (Revised) RHB Benedict (Clin Neuropsych 1994; Psychol Assess 1996; Psychol Assess Resources 1997). Benedict et al. Clin Neuropsychol 2002; 16: 381-97 12

  13. BICAMSBrief International Cognitive Assessment for MS Battery: SDMT CVLT-II, first recall trials BVMTR, first recall trials BICAMS committee meetings and website are sponsored by Bayer Healthcare

  14. MS patients compared to healthy controls on BICAMSParmenter et al., JINS 2010;16:6-16

  15. Raw score to scaled score conversionParmenter et al., JINS 2010;16:6-16

  16. BICAMS committee meetings and website are sponsored by Bayer Healthcare

  17. BICAMSBrief International Cognitive Assessment for MS • Identify a brief assessment tool for cognition in MS • can be used by health care professionals who are not cognitive specialists • has international validation • Specify an international validation protocol that can be implemented in any country BICAMS committee meetings and website are sponsored by Bayer Healthcare

  18. BICAMSBrief International Cognitive Assessment for MSinternational validation protocol • Step 1, Standardization and Translation of Test Stimuli. • Step 2, Standardization and Translation of Test Instructions • Step 3, Normalization • Step 4, Test-Retest Reliability • Step 5, Criterion-Related Validity Benedict et al., BMC Neurology (submitted) BICAMS committee meetings and website are sponsored by Bayer Healthcare

  19. BICAMSBrief International Cognitive Assessment for MS:National Validations

  20. BICAMSBrief International Cognitive Assessment for MS • Identify a brief assessment tool for cognition in MS • can be used by health care professionals who are not cognitive specialists • has international validation • Specify an international validation protocol that can be implemented in any country • Agree guidelines on test-retest timing and clinically significant change BICAMS committee meetings and website are sponsored by Bayer Healthcare

  21. Screening tests Screening tests Brief Batteries Brief Batteries Intermediate length Batteries Comprehensive Batteries Assessment of Cognition Routine in the office 0 mins Routine in the clinic BICAMS 15 mins 45 mins Routine NP exam 90 mins Differential diagnosis Disability questions Rehabilitation programs 120 mins 21

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