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ARMOR Optimize

ARMOR Optimize. Chad Byers - Project Manager Brendan Grebur - Domain Expert / Customer Liaison Rory Hool - Project Facilitator Caitlin Russ - Artifacts Manager. What Optimization Means.

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ARMOR Optimize

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  1. ARMOR Optimize Chad Byers - Project Manager Brendan Grebur - Domain Expert / Customer Liaison Rory Hool - Project Facilitator Caitlin Russ - Artifacts Manager

  2. What Optimization Means • Finding solution(s) to maximize / minimize a set of defined criteria, subject to a set of constraints, for a specific problem • Problem • Improving a patient's quality of life by reducing polypharmacy interactions • Criteria • Increasing or Reducing • Bodily aspects (appetite, balance, vision, etc.) • Constraints • Drug constraints • Increase / Reduce / Remove / No Alteration • Condition constraints • "To treat or not to treat"

  3. The Basic Terminology Continuity of Care Record (CCR) Body Measurements  Afflicting Conditions Drugs (Past / Present)  Drugs Prescribed and Over-the-counter (OTC)  Frequency and Dosage Set of affected body aspects and a quantitative effect Increase or Decrease Condition Treated by a group of drugs Body Aspect Similar to side effects Appetite, vision, balance, depression, diarrhea Treatment Plan  Current: Existing prescribed treatment plan Recommended: Optimized treatment plans for review

  4. The Extended Terminology Goal Profile A collection of: Body aspects each denoting a desired change Other Goal Profiles Example: Better Balance { vision+ , dizziness- , lightheaded- } Goal Set An accumulation of weighted: Goal profiles Individual body aspects each with denoted change   Example: (5 * Better Balance ) + (3 * depression-)

  5. Use Case Diagram

  6. Web Interface Front-end Class Diagram

  7. System Back (Server) - Evolutionary Computation • Modification Encoding • Representation of adjustments to current treatment plan • Treatment Adjustment ("Gene") • Per drug containing: • Increase / Decrease / Reduce / No Alteration • Population • Encodings competing to provide the best solution • Selection Protocol • Roulette • Tournament* • Rank

  8. Evolutionary Computation Back-end Class Diagram

  9. Evolutionary Optimization Algorithm

  10. System Front (Client) Statechart

  11. System Back (Server) Statechart

  12. Sequence Diagram:Creating And Using New Goal Profile

  13. Sequence Diagram:Evolutionary Optimization

  14. Sequence Diagram:Display and Review of Treatment Plans

  15. Sequence Diagram: Goals Not Specified for Optimization

  16. Prototype Demo • High Level Features of User Interface • Upload CCR with Analysis Results • Select drug / condition constraints • Create custom Goal Profile • Select Goal Profiles and Body Aspects for Goal Set • Select Weighting Criteria for members of Goal Set • View Optimization summary • View Optimized treatment plans • Save / Delete treatment plans Web Prototype

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