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Stent Redesign . Whit Miller BME Senior Design Spring 2001. In 1999, US Physicians performed over 500,000 PCTA procedures involving a stent placement. Within one year of de- ployment, 50% of stents illicit a restenosis. Market Analysis. Making a Better Mousetrap.

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Stent redesign

Stent Redesign

Whit Miller

BME Senior Design

Spring 2001


Market analysis

In 1999, US Physicians performed over 500,000 PCTA

procedures involving

a stent placement

Within one year of de-

ployment, 50% of stents illicit a restenosis.

Market Analysis


Making a better mousetrap
Making a Better Mousetrap

  • Current stents are bare metal

  • A covered stent would have at least two advantages

  • Limit SMC proliferation at the deployment site

  • Expedite endothelialization


Ses vs balloon deployed
SES Vs Balloon-Deployed

  • Self-Expanding Stents are considered superior for two reasons

  • Maximize deployment precision

  • Minimize catheterization time


Current technology
Current Technology

  • Best of the Current Covered SESs

  • The Wallgraft and Corvita


The need for improvement
The need for improvement

  • Current covered SES have limited proven ability to prevent restenosis

  • Neurovascular interventionalists have limited options for cerebral stenting


Project goals
Project Goals

  • Select a stent covering

  • Covering will be mated with superior stent design

  • Investigate commercial polymers and cadaveric decellularlized material

  • Subject covering to filtration, deployment constraints


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