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Biozip Suture Group 24 Katie Good and Emily Schaefer

Biozip Suture Group 24 Katie Good and Emily Schaefer. Advisors: Bruce Beyer, M.D. Paul King, Ph.D. Problem Statement. Requirement Bioabsorbable zip-tie suture Performance Criteria Unidirectional Tension Maintain suture tied and tight Primary Objective

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Biozip Suture Group 24 Katie Good and Emily Schaefer

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  1. Biozip SutureGroup 24Katie Good and Emily Schaefer Advisors: Bruce Beyer, M.D. Paul King, Ph.D.

  2. Problem Statement • Requirement • Bioabsorbable zip-tie suture • Performance Criteria • Unidirectional Tension • Maintain suture tied and tight • Primary Objective • Create suture allowing tactility and ease during deep tissue procedures

  3. Current Technique • Current sutures - application of tension in opposite directions • Gynecological procedures - confined areas • Difficult to apply tension • Suture integrity compromised

  4. Our Approach • Require tension in one direction • Twist tie design • Beaded model design Clamp & Fuse

  5. Twist Tie • Material Considerations • Dexon vs. Vicryl • Coated vs. Non-coated • Monofilament vs. Braided • Small gage used during OB-Gyn procedures • Material properties after heating • Temperature • Exposure time

  6. Beaded Model • Material • Shape memory • Heat shrink • Distance between beads • Manufacturing • Injection molded • 3-D printing • Prototype/Testing

  7. Testing Our Sutures • Instron Tensiometer • BlueHill software • Ideal for < 2kN • 0.4% accuracy • Output • Tensile strength • Elongation • Breaking Point • Located in VUMC SDRCC

  8. Materials • Tensile Strength (0-gauge) • Polyglactin 910 • (Vicryl) ~ 95 N • Polyglycolic Acid • (Dexon) ~85 N

  9. Current Status • Fused 4-0 vicryl w. hair straightener • Need more samples  optimize fuse • Obtain from Hospital Supply • Meeting – Dr. DasGupta • Learn to use tensiometer • Test samples • Budget

  10. Budget • Hemostat • 7.25” ~ $19.00 • Suture material • Vircyl 2-0 ~ $55 – 120 (3 dozen) • Dexon 5-0 ~ $192 (dozen) • Develop/purchase heating element • Hair straighteners ~ $20 – 65 • Total ~ $95 – 205

  11. Future Work • Develop/purchase a heating element • Test sutures in SDRCC on tissue/pedicles • Dr. Beyer test procedure for ease of application

  12. References • Bourne, R.B., MD, FRCSC, Bitar, H. MD, Andreae, P.R., BSC, Martin L.M., MB, BS, Finlay, J.B., PhD, & Marquis, F., MD FRCSC (1988). In-vivo comparison of four absorbable sutures: Vicryl, Dexon Plus, Maxon, and PDS. The Canadian Journal of Surgery, 31(1), 43-45. • von Fraunhofer, J. A., Storey, R. S., Stone, I. K., & Masterson, B. J. (1985). Tensile strength of suture materials. Journal of Biomedical Materials Research, 19(5), 595-600.

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