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Biozip Suture Group 24 Katie Good and Emily Schaefer

Biozip Suture Group 24 Katie Good and Emily Schaefer. Advisors: Bruce Beyer, M.D. Paul King, Ph.D. Problem Statement. Gynecological procedures - confined areas Difficult to apply tension Suture integrity compromised Alternative method for closing tissue or pedicles

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Biozip Suture Group 24 Katie Good and Emily Schaefer

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  1. Biozip SutureGroup 24Katie Good and Emily Schaefer Advisors: Bruce Beyer, M.D. Paul King, Ph.D.

  2. Problem Statement • Gynecological procedures - confined areas • Difficult to apply tension • Suture integrity compromised • Alternative method for closing tissue or pedicles • Require tension in one direction

  3. Desired Qualities • Bioabsorbable • Tensile strength • 80 – 100 N • Degradation time • 3 -4 weeks • Unidirectional Tension • Maintain suture integrity • Simple closure procedure

  4. Design Significance • C-section - 1.2 Million surgeries/year • Hysterectomy - 600,000 surgeries/year • Improved suture design will • Decrease surgery time and therefore potential for infection • Easier closure procedure • Greater confidence in suture integrity

  5. Competing Technologies • Traditional suture • tension in opposite directions, form knots • Laparoscopic technique • Quik-Stitch® • LIGA – CLIPS (Ethicon) • Metal surgical clips • Electrocautery • Sealing pedicles http://www.paresurgical.com

  6. Twist Tie Approach • Vicryl • 0 and 2 gauge • Braided • Coated • Dexon • 3 gauge • Braided • Uncoated Clamp & Fuse

  7. Budget • Hemostat • 7.25” ~ $21.00 • Suture material • Vicryl 0 (qty 6) ~ $1.57 ea • Vircyl 2-0 (qty 6) ~ $1.50 ea • Dexon 3-0 (qty 3) ~ $15.96 ea • Total ~ $87.30 • Heated tweezers ~ $209

  8. Fusing Sutures • Dexon • did not fuse • Vicryl • 3 sutures per trial • Trials

  9. Testing Our Sutures • Instron Tensiometer • BlueHill software • Ideal for < 2kN • 0.4% accuracy • Output • Tensile strength • Elongation • Breaking Point • Located in VUMC SDRCC http://www.instron.us/wa/products/universal_material/5840.aspx

  10. Heating Element • Heated Tweezers • Wax Connections • Pedal controls power to tweezers • No specific temperature listed http://www.waxconnections.com/Page11.html

  11. Current Status • Purchased sutures from Hospital Supply • Fused Vicryl sutures w. hair straightener • Meeting – Dr. DasGupta on Thursday • Learn to use tensiometer • Test samples • Meet with Dr. Beyer • Ask to tie sutures for comparison testing

  12. Future Work • Research other heating element options • Research current surgical heating techniques • Dr. Beyer test procedure for ease of application • Paper and poster

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