Repair of DS BREAKS - PowerPoint PPT Presentation

Repair of DS BREAKS

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DS Break Repair Pathway'. Retrieve Sequence information from undamaged DNAUses recombinationMutants defective in recombination are UV sensitive (inefficient repair). DS DNA BREAKS (or DSBs)VERY toxicMust be dealt withHigh Mutagenic potentialExploit DSBs for immunoglobulin rearrangements. Or

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Repair of DS BREAKS

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