'Rna editing' presentation slideshows

Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome

1.19k views • 92 slides

LIVER

LIVER. Glucose. Ketone bodies. Glucose. Fatty acids. Glycerol. VLDL. Glucose can can NOT be made from fatty acids. TCA cycle. FED FASTING. Roles of Various Tissues in TG metabolism: MUSCLE. Glucose. Fatty acids. Ketone bodies. Glucose. Acetyl-CoA. Lactate (anaerobic).

1.04k views • 50 slides

Introduction to Next-Generation Sequencing (NGS) Analysis of Transcription using RNA- Seq

Introduction to Next-Generation Sequencing (NGS) Analysis of Transcription using RNA- Seq Dr. Robert Boissy SWH2048 rboissy@unmc.edu. NGS instruments and data analysis software RNA- Seq overview mRNA gene expression mRNA transcript isoforms mRNA special cases miRNA gene expression.

459 views • 44 slides

Talk to a partner: DNA Recap

Talk to a partner: DNA Recap. RNA = Ribonucleic Acid Single stranded Contains the sugar RIBOSE instead of deoxyribose Contains the nitrogen base URACIL instead of thymine.

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Mutations and Epimutations

Mutations and Epimutations. A story of two cultivars and their children. Matteo Pellegrini. Nipponbare and 93-11. Nipponbare : Oryza sativa japonica Primarily Japan, China, Indonesia Agronomic differences: Days to heading. 93-11 Oryza sativa indica India, Bangladesh, Nepal, China

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PREditor P redictive R NA Editor for Plant Mitochondrial Genes

PREditor P redictive R NA Editor for Plant Mitochondrial Genes. Jeff Mower. What is RNA Editing? A process that alters the RNA sequence Nt insertion, deletion, or conversion Does not include RNA maturation processes. RNA Editing in Plants Occurs in mitochondria and chloroplasts

387 views • 32 slides

Regulating gene expression Goal is controlling Proteins How many? Where? How active?

Regulating gene expression Goal is controlling Proteins How many? Where? How active? 8 levels (two not shown are mRNA localization & prot degradation). mRNA PROCESSING Primary transcript is hnRNA undergoes 3 processing reactions before export to cytosol

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Targeted Sequencing of Human Genomes, Transcriptomes, and Methylomes

Targeted Sequencing of Human Genomes, Transcriptomes, and Methylomes. Jin Billy Li George Church Lab Harvard Medical School jli@genetics.med.harvard.edu. Genetic Loci X Sample Size = Information. PCR seq Mass-spec. SNP array. # samples. Shotgun seq RNA-seq ChIP-seq. # genetic loci.

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Biology and Biochemistry 2019-2020 Research Projects

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12-3 Protein Synthesis

12-3 Protein Synthesis. Double stranded Sugar = deoxyribose Thymine (no Uracil) Stays in nucleus One type Same copy in the cell all the time. Single stranded Sugar = ribose Uracil (instead of Thymine) Nucleus & cytoplasm 3 types (mRNA, tRNA, rRNA) Disposable copies. DNA vs. RNA.

430 views • 29 slides

12-3 Protein Synthesis

12-3 Protein Synthesis. Double stranded Sugar = deoxyribose Thymine (no Uracil) Stays in nucleus One type Same copy in the cell all the time. Single stranded Sugar = ribose Uracil (instead of Thymine) Nucleus & cytoplasm 3 types (mRNA, tRNA, rRNA) Disposable copies. DNA vs. RNA.

381 views • 29 slides

Key points: summarized from chapter 14

Key points: summarized from chapter 14. RNA processing. Outline: we will focus on mRNA processing. Overview of the Central Dogma Introns versus exons What is a codon Steps of pre-mRNA processing Eukaryotes versus prokaryotes. 3 steps of mRNA processing occurs in the nucleus of eukaryotes.

395 views • 26 slides

?70, ?32, ?54

?. ?70, ?32, ?54. Sp1. HSTF.

347 views • 23 slides

RNA

425 views • 17 slides

RNA 3 major classes: mRNA 2-5% tRNA 10-15% rRNA 80-85%

RNA 3 major classes: mRNA 2-5% tRNA 10-15% rRNA 80-85% mRNA - number of different mRNAs in a cell can range from 100s to 1000s & sizes can differ from 100s to 1000s nucleotides In bacteria, mRNA synthesized, utilized and degraded continually so constant turnover, t1/2 of mRNA ~2 min

302 views • 17 slides

A potential therapy for ALS

A potential therapy for ALS. June 2, 2013. Content. Brief introduction about ALS and the field Proposal First an overview of how each component affects disease pathogenesis followed by my therapy idea. What is ALS?. First described in 1869 by Dr. Jean Martin Charcot

377 views • 17 slides

RNA, Transcription, and Translation

RNA, Transcription, and Translation. How we get from DNA to proteins. RNA (Ribonucleic Acid). RNA is very similar to DNA, but with three main differences: The backbone of RNA uses a ribose sugar molecule in place of the deoxyribose sugar molecule that DNA uses

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Eucaryotic Gene Expression

Eucaryotic Gene Expression. Lecture 15. Key Eucaryotic Features. DNA is wrapped around chromatin Nucleosomes made of histone proteins Tightly packaged and organised into chromosomes Relatively inaccessible DNA lives in the nucleus mRNA has to be transported out for translation

157 views • 14 slides

Project

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The slime mold Physarum polycephalum edits its own RNA (see figure).

Possible Sequence Motifs for RNA editing in slime molds Ralf A. Bundschuh (Ohio State University) DMR 0706002. The slime mold Physarum polycephalum edits its own RNA (see figure). It always does so at the same place in the sequence. How does it know where?

181 views • 2 slides