'Genotype frequencies' presentation slideshows

Biometrical Models and Introduction to Genetic Analysis

Biometrical Models and Introduction to Genetic Analysis. Pak Sham, University of Hong Kong 4 th March 2019 The 2019 International Workshop on Statistical Genetics Methods for Human Complex Traits. What is biometrical genetics?.

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Hunting for Genes with Longitudinal Phenotype Data Using Stata Stata Conference Boston 2010 July 15, 2010

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Molecular Markers

Molecular Markers. DNA & PROTEINS mtDNA = often used in systematics; in general, no recombination = uniparental inheritance cpDNA = often used in systematics; in general, no recombination = uniparental inheritance Microsatellites = tandem repeats; genotyping & population structure

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Genetic analysis requires variation at loci, variation of markers (polymorphisms)

Genetic analysis requires variation at loci, variation of markers (polymorphisms). How the variation is structured will tell us Does the microbe reproduce sexually or clonally Is infection primary or secondary

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Ch. 22/23 Warm-up

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Statistical Methods for Quantitative Trait Loci (QTL) Mapping

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Evolution is: Change in allele frequencies across generations.

Evolution is: Change in allele frequencies across generations. Form of a gene proportions. FREQUENCIES ALWAYS SUM TO 1. Frequency of students who prefer Foss. Frequency of students who prefer the new Bobs. Frequency of students who prefer Dana.

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Evolution of Populations

Evolution of Populations. DO NOW. Is evolution random or non-random? Be prepared to discuss. . DO NOW. Hand in Chapter 22 Homework and signed contract (place in folder marked with your class period)

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One-locus diploid model

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Hardy-Weinberg Equilibrium

Hardy-Weinberg Equilibrium. In order for a population to undergo change it must have genetic variation

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One way to test these theories is to look at th number of silent vs.

Neutral or Selectionist?. One way to test these theories is to look at th number of silent vs. non-synonymous substitutions over a given region of DNA are silent point mutations in DNA (no effect on phenotype) more common or less common than non-synonymous changes?

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POPULATION GENETICS

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Selection for Scrapie resistance based on PrP polymorphism

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Probability in genetics

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Hardy-Weinberg Equilibrium Review

Hardy-Weinberg Equilibrium Review. By Sean McGrath. Hardy-Weinberg Theorem. Laid out in 1908 by the two scientists who independently discovered it States that frequencies of alleles within a population that is not evolving will remain constant from generation from generation

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Hardy-Weinberg Lab

Hardy-Weinberg Lab. Taste Testing. PTC. Phenylthiocarbamide Compound contains sulfur Harmless chemical Found in Brassica family of plants Cabbages, brussel sprouts, kale Gives a slight bitterness. Tasting PTC. Dominant: Tasters Find low concentrations of PTC extremely bitter

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Helen Stuart, Cardiff

How can we use Hardy-Weinberg equilibrium to calculate carrier frequencies of recessive diseases if we know the proportion of people who are affected?. Helen Stuart, Cardiff. Essay plan. Description of Hardy-Weinberg principle (HWP) Allele frequencies: p+q=1

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Population Genetics

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Population Genetics

Population Genetics. Measuring Evolutionary Change Over Time. I. Evolution as Genetic Change. Trait : An inherited physical characteristic Gene : An inherited segment of DNA on a chromosome that codes for a trait Allele : One of a number of different forms of a gene for a particular trait

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HIV-1 Infection Vs HIV-1 Antibody-Negative Individuals And Genotypic Markers

HIV-1 Infection Vs HIV-1 Antibody-Negative Individuals And Genotypic Markers. Jacinta Gaitor 2/15/02. Determination of Genotype Frequency among HIV-1 Infected versus Non-infected Individuals. Genomic DNA was screened by using 170 mapped polymorphic loci.

204 views • 4 slides