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BPS 502 Chapter 15

BPS 502 Chapter 15

BPS 502 Chapter 15. Cell Communication Signaling through enzyme-linked cell surface receptors. Reading Assignment. MBC, Chapter 15 Levitzki A. 2003, EGF Receptor as a Therapeutic Target. Lung Cancer , 41: S9-S14. Objectives.

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749 views • 56 slides
Signaling Pathways that Depend on Regulated Proteolysis

Signaling Pathways that Depend on Regulated Proteolysis

Signaling Pathways that Depend on Regulated Proteolysis. 7 May 2007. Identified through genetic studies in drosophila. Highly conserved in evolution and are very important in animal development. Wnt Notch Hedgehog NF ?B. Wnts.

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1.3k views • 54 slides
Changes in Mechanical Stress- Bone Adaptations

Changes in Mechanical Stress- Bone Adaptations

Changes in Mechanical Stress- Bone Adaptations. Wolff's Law (1890s) - Bone remodels according to functional demands Not tested until the 1960s Exercise as a health therapeutic agent Spaceflight. BONE and Spaceflight. Bone Loss with Spaceflight.

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411 views • 21 slides
Signaling to PROGRAM cell death (Apoptosis)

Signaling to PROGRAM cell death (Apoptosis)

Signaling to PROGRAM cell death (Apoptosis). Apoptosis is a cell mechanism used to eliminate cells that are unnecessary to or that contain mutations that are dangerous to the body . Loss of the ability to undergo apoptosis leads to cancer. . 1. Phenotypes of apoptosis:

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730 views • 19 slides
Chapter 15 Cytoskeleton: Regulation by Accessory Proteins

Chapter 15 Cytoskeleton: Regulation by Accessory Proteins

Chapter 15 Cytoskeleton: Regulation by Accessory Proteins. Microtubules are nucleated by a protein complex containing g -tubulin. Dynamics of cytoskeletal filaments: Length Stability Number Geometry. g- tubulin ring complex ( g -TuRC): minus end. Subcomplex: accessory proteins

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425 views • 18 slides
Biochemical Mechanisms for Long-term Information Storage at the Cellular Level

Biochemical Mechanisms for Long-term Information Storage at the Cellular Level

Biochemical Mechanisms for Long-term Information Storage at the Cellular Level. From Mechanisms of Memory by J. David Sweatt, Ph.D. Protein Synthesis Dependence of L-LTP. Kang et al. (2001) Cell 106:771-783. PO 4. PO 4. The CREB/CRE Gene Regulation System. acetylation. pKAF. Histone.

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276 views • 11 slides
(from Kerfoot & Kubes, J Immunol 2002; 169: 1000)

(from Kerfoot & Kubes, J Immunol 2002; 169: 1000)

Anti-P-selectin alone blocks rolling, not other selectins. Expression is seen in brain and spinal cord in EAE. Levels are low, but increased. (from Kerfoot & Kubes, J Immunol 2002; 169: 1000). P-selectin blocking before assay inhibits both rolling and adhesion at peak disease (4d)

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223 views • 11 slides
Vascular Endothelial Cell Interactions and Signaling

Vascular Endothelial Cell Interactions and Signaling

Vascular Endothelial Cell Interactions and Signaling. SIGMA-ALDRICH. Vascular Endothelial Cell Interactions and Signaling

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119 views • 2 slides

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