'B cell' presentation slideshows

The Molecular Genetics of Immunoglobulins

The Molecular Genetics of Immunoglobulins. Recall Structure . Numerous V region genes are preceded by Leader or signal sequences (60-90 bp ) exons interspersed with introns .

724 views • 62 slides

DNA and Chromosome Structure

DNA and Chromosome Structure. Chromosomal Structure of the Genetic Material. The Essential Structure of DNA. The Replication Challenge. Size of an average human chromosome 130 million bp Rate of replication ~ 50 bp per sec Fidelity of replication. Replication of the Genetic Material.

805 views • 54 slides

Germinal Center Response

Germinal Center Response. Hypermutation and selection. Affinity of Serum Ig increases during an immune response Somatic mutation in Ig V region genes, in response to protein, in B cells in mouse spleen does not start until after the onset of Ab production

955 views • 48 slides

Leukemias

Leukemias. Jan ?eromski Pathology 2010/2011. Definition and two main lineages. Malignant proliferation of white cells of the hematopoietic system with infestation of blood and usually bone marrow. Lymphoid and myeloid leukemias. Cell origin and pathogenesis.

824 views • 45 slides

TB Pathogenesis

TB Pathogenesis. Stacey Rizza, M.D. Disclosures. None. Objectives. Explain how M. tuberculosis is transmitted Describe the immune response to M. tuberculosis Understand the targets of immunotherapies for M. tuberculosis.

985 views • 44 slides

AUTOIMMUNITY

AUTOIMMUNITY. Dr. Anand Kumar & Dr. R.. A. Siddique N.D.R.I., Karnal (Haryana) India, 132001 Email-riazndri@gmail.com. Self/Non-self Discrimination. Autoimmunity is a problem of self/non-self discrimination. Autoimmunity.

1.06k views • 42 slides

Hypersensitive Reactions

Hypersensitive Reactions. 1. Type I Hypersensitivity 2. Type II Hypersensitivity 3. Type III Hypersensitivity 4. Type IV Hypersensitivity. 1. Basic concepts

692 views • 32 slides

Immunoglobulins: Structure and Function

Immunoglobulins: Structure and Function. -. +. albumin. Amount of protein. globulins. ?. ?. ? 1. ? 2. Immune serum. Ag adsorbed serum. Mobility. Immunoglobulins:Structure and Function.

1.77k views • 31 slides

Alterations in Immune Function

Alterations in Immune Function. Ball and Bindler Donna Hills APN EdD ( c). Signs and symptoms. In children, immune disorders are often non-specific. Why? How do children fight off infection? How are their immune systems anatomically different from the adult?. Pediatric Differences.

824 views • 30 slides

Minimal change disease and treatment with steroids

Minimal change disease and treatment with steroids . 7/24/2007 Zae Kim, MD. Clinical Question. Why does MCD respond to steroid? Why do they develop resistance?. Introduction. Most common cause of the nephrotic syndrome in children

735 views • 28 slides

Chapter 37

Chapter 37. The Lymphatic System and Immune Response. Lymphatic System. Lymphatic vessels Lymphatic tissues Tonsils Primary lymphatic organs Thymus and Bone marrow Secondary lymphatic organs Lymph nodes, spleen. Lymphatic System. Lymphatic System. Lymph Fluid lost from the capillaries

542 views • 27 slides

Immunology

Immunology. BIT 120 Chapters 11. Immunity. Ability of body to defend against infectious agents, foreign cells, abnormal cells Antigen: foreign substance/molecule which elicits an immune response ? from virus, bacteria, mold, cancer, pollen

449 views • 22 slides

Immune System Disorders

Immune System Disorders. What is an allergy anyway?. Hypersensitivity Reactions. Response to antigens (allergens) leading to damage Require sensitizing dose(s). Type I (Anaphylactic) Reactions. Involve IgE antibodies Localized: Hives or asthma from contact or inhaled antigens

555 views • 20 slides

Russell J. Mumper, Ph.D.

Russell J. Mumper, Ph.D. Director: Center for Nanotechnology in Drug Delivery at the University of North Carolina - Chapel Hill. Moving Toward Clinical Investigation with Pharmaceutically Engineered Lipid-Based Nanoparticles. Russell J. Mumper, Ph.D.

393 views • 20 slides

Announcements

Announcements. Case Studies: There are three case studies that were provided: Case 10, 11, & 12. Please do case study 10 & 12 only. Case 11 was provided for information that may assist with Case 12. Due Feb 15, 2008 Exam 1: Question 20: correct answer was B and E.

319 views • 18 slides

Chapter 3

292 views • 18 slides

Heavy Chain Rearrangement

Heavy Chain Rearrangement. The B cell receptor is made up of two kinds of proteins, the heavy chain ( Hc ) and the light chain ( Lc )., Each of these proteins is encoded by genes that are assembled from gene segments.

318 views • 16 slides

Antibody & Western B lotting

Antibody & Western B lotting. Antibodies in the Immune System. Structure : 2 heavy chains + 2 light chains Disulfide bonds 2 antigen binding sites Isotypes: IgG, IgM, IgA, IgE, IgD. Antibodies are produced by B lymphocytes. Clonal Selection

231 views • 14 slides

Immune System

Immune System . By: Perri Glover, Mary Beth Eaves, && Meagan Riggins. Definition. A system of biological organ that organs that protect against disease by identifying and eliminating harmful pathogens from the body. This system is also considered the lymphatic system.

254 views • 12 slides

Study Design

145 views • 3 slides