Prednisone. Jessica Skutnik Nur 555. Objectives. The purpose of this presentation is to understand the indications for prescribing prednisone, the dosing schedule, side effects to be aware of, and ways to possibly avoid these side effects. Prednisone.
18-36 hours in tissue
Situations where dose adjustment may need to be closely monitored include:
Every other day dosing does NOT protect:
AND patients may have flare ups on “off” days
ex: SLE often flares during pregnancy, the SLE-associated arthritis can be controlled in the 1st and 2nd trimester with acetaminophen or NSAIDs
HOWEVER: other manifestations such as lupus nephritis or severe thrombocytopenia may require medication that is contraindicated in pregnancy-in this situation higher doses of prednisone are safer to use.
Glucocorticoids. (2002). In Erwin Kastrup (ed.) Drug Facts and Comparisons. St. Louis, MO. Facts and Comparisons.
Prenisone Oral (2003). Retrieved March 19, 2006 from http://www/nlm.nih.gov/medlineplus/print/druginfo/medmaster/a601102.html
Saag, K., Curtis, J. (2003). Use of glucocorticoids in arthritis: 20 clinical pearls maximizing the benefits, minimizing the complications. The Journal of Musculoskeletal Medicine, 20, 425-433.