Mri of gene expression
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MRI of Gene Expression. Assaf A Gilad , Guanshu Liu, Michael T. Mcmahon, Piotr Walczak, Amnon Bar Shir, Anna Munsey, Segun Bernard, Xiaolei song, Jeff W.M. Bulte and Peter C.M. van Zijl. Assaf A. Gilad, Ph.D. Assistant Professor of Radiology

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MRI of Gene Expression

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Mri of gene expression

MRI of Gene Expression

Assaf A Gilad, Guanshu Liu, Michael T. Mcmahon, Piotr Walczak, Amnon Bar Shir, Anna Munsey, Segun Bernard, Xiaolei song, Jeff W.M. Bulte and Peter C.M. van Zijl.

Assaf A. Gilad, Ph.D.

Assistant Professor of Radiology

The Russell H. Morgan Department of Radiology and Radiological Science

Division of MR Research and Institute for Cell Engineering

Johns Hopkins University School of Medicine


Reporter genes

Reporter genes

  • Using molecular biology tools we can place in front of the promoter different gene that have some properties that can be detected using microscope, CCD camera, PET or MRI.

Gilad AA, Winnard PT Jr, van Zijl PC, Bulte JW. NMR Biomed. 2007 May;20(3):275-90.


In vivo imaging of lrp in 9l brain tumors

In vivo imaging of LRP in 9L brain tumors

Control

Tumor

In this presentation we discuss two putative reporter genes that can be imaged with MRI.

Both of the genes are based on Chemical Exchange saturation transfer contrast mechanism.

Tumor

LRP

16

%

8

Gilad AA, et al. Nat Biotechnol 2007;25(2):217-219.

Gilad AA, et al. Nat Biotechnol 2007;25(2):217-219.


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