Gene Expression. Early evidence indicating most genes specify the structure of proteins Garrod’s work on inborn errors of metabolism in early 1900s Beadle and Tatum’s work with Neurospora mutants in the 1940s. An “inborn error of metabolism”. Mutations affecting biochemical pathways.
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An“inborn errorof metabolism”
Overview of transcription and translation
Synthesis of mRNA
Three representations of a tRNA molecule
Initiation of translation in bacteria
Elongation cycle in translation
Termination of translation
Coupled transcription and transla-tion in bacteria
Infection cycle of an RNA tumor virus