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Digestive System II. Liver, Gallbladder, Pancreas. Liver. Extremely important accessory organ of the digestive system Main functions of the liver are: Metabolic regulation 200 metabolic reactions All blood from the digestive system is processed by the liver

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digestive system ii

Digestive System II

Liver, Gallbladder, Pancreas

liver
Liver
  • Extremely important accessory organ of the digestive system
  • Main functions of the liver are:
  • Metabolic regulation
    • 200 metabolic reactions
    • All blood from the digestive system is processed by the liver
    • Liver removes toxins and waste products from the blood
  • Hematological regulation
    • Removal of old RBC’s
  • Synthesis and secretion of bile
liver cells
Liver cells
  • Liver cells are called HEPATOCYTES
  • In the liver, these cells are arranged in irregular plates called LOBULES
  • Blood circulates through and around these cells entering via branches of the portal vein and hepatic artery
  • Blood leaves the lobules via the central vein
gallbladder
Gallbladder
  • Located in a recess in the visceral surface of the right lobe of the liver
  • Stores and concentrates bile made in the liver
  • Function of bile is to emulsify fats in the diet so that the fat can be digested
  • Bile is secreted into the duodenum via the common bile duct
transport of bile
Transport of Bile
  • Bile is secreted into small channels in the liver called bile canaliculi
  • The canaliculi form larger bile ductules
  • The ductules form the right and left hepatic duct which fuse to form the common hepatic duct
  • The cystic duct joins with the common hepatic duct to form the common bile duct
pancreatic secretions
Pancreatic Secretions
  • Bicarbonate – neutralizes acidic chyme
  • Amylase – continues carbohydrate digestion
  • Protease enzymes
    • Trypsin which activates
    • Chymotrypsin and Carboxypeptidase
  • Lipid enzymes
    • Colipase and Phospholipase
histology of the pancreas
Histology of the Pancreas
  • Pancreas is composed of:
  • 1. Pancreatic acini cells
    • Exocrine cells
    • Secrete the pancreatic enzymes into the duodenum
  • 2. Islet cells
    • Endocrine cells
    • Secrete insulin
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