Gregory R. Pacheco Castleman Disease Research Laboratory. Opening The Way To Novel Therapies for Castleman Disease. What is Castleman Disease?. Discovered by Dr. Benjamin Castleman in 1956 “Benign” enlargement of lymph nodes (not cancer)
Opening The Way To Novel Therapies for Castleman Disease
(microscopy) vs. Mixed Cellularity type
Brandt et al, JCI 86, 1990
Before therapy After 2 months After 6 months
For diagnosis, research, therapy, and long-term follow-up
Gregory R. Pacheco Multicentric CDThe Gregory R. Pacheco Castleman Disease Research Laboratory
Studies the etiology of Castleman Disease, with the goal of shedding light on its cause and leading to more efficacious treatments and the possibility of a cure.
This powerful instrument is used for the identification and characterization of individual cells in a mixed population.
The Pacheco Lab houses the largest bank of Castleman Disease patient samples in the world, and a suite of equipment for tissue culture and molecular studies.
First CD conference in Santa Fe, New Mexico
Tissue/Serum Bank, consensus for methods of procurement, triaging, studies to be performed
NIH (Orphan Disease), IMF, MMRF, LLS, Pharma