Research and Data showing the link between Lyme disease/ Borrelia and Autism Spectrum Disorder

1. Research and Data showing the link between Lyme disease/Borrelia and Autism Spectrum Disorder LIA Foundation 1771 Honors Lane Corona, CA 92883 1-877-650-4046 www.liafoundation.org

2. Lets compare numbers.. Top 15 states for Autism (2005) Top 15 states for Lyme disease (2005) Delaware Connecticut New Jersey Massachusetts Pennsylvania New York Wisconsin Maryland New Hampshire Maine Minnesota Vermont Rhode Island Virginia West Virginia • Minnesota • Oregon • Maine • Indiana • Massachusetts • Connecticut • Michigan • Maryland • Rhode Island • Wisconsin • California • Pennsylvania • New Jersey • Hawaii • Virginia 11 Out of the top 15 states overlap for incidence of Autism and Lyme

3. Informal Lyme-Autism Study Testing Methods/Criteria • IFA and Western Blot IgG and IgM were performed by IgeneX Inc. • Patients were NOT screened. The criteria was that the child needed an autism, pdd-nos or asperger’s diagnosis PLUS some sort of immune dysfunction. • It was attempted to get matching controls for each child. • Samples were taken from CA, NV, AZ, IL,NY, NJ, WI, TX.

4. Informal Lyme-Autism Study Testing Methods/Criteria • 19 autistic samples were obtained and 5 controls • Positive result would indicate one or more borrelia specific bands testing positive. • Ambiguous result would indicate 2 or more indeterminate bands which are borrelia specific. (this would indicate a possible re-test after a treatment trial.)

5. Informal Lyme-Autism Study

6. What does 26.32% of autistic children affected mean? At least…… 132,000 children with autism could be affected by Lyme Disease (borrelia bacteria) Where are they, why aren’t they being diagnosed and treated?

7. Autism samples from different clinics in Northern California, New York, New Jersey and Connecticut. – Vojdani – 2007 as presented at the Lyme-Autism Connection Conference. 7

8. Gestational Lyme Disease Case Studies of 102 Live Birthsby Charles Ray Jones, M.D., Harold Smith, M.d. Edina Gibb, and Lorraine Johnson, JD, MBA • 102 children with gestational Lyme Disease • Mothers had either untreated or partially treated LD • Children were diagnosed between the ages of 1 – 5 yrs old • Symptoms were present in infants but overlooked until they gradually progressed in frequency and severity. Lyme Times, 2005 Summer Edition

9. Results % of children with the following symptoms.. • 27% - Cognitive delay • 21% - Speech delay • 19% - reading/writing problems • 17% - articulation delay • 13% auditory/visual processing disorder • 12% Word selectivity • 8% Dyslexia • 23% Anger or Rage • 13% Aggression or Violence • 11% OCD • 54% Irritability and Mood Swings • 13% Emotional Problems • 13% Depression • 7% - Suicidal thoughts • 56% - ADHD • 36% - Sensory sensitivity manifested as hyperacuity • 43% Photophobia • 9% Motion Sickness • 23% Tactile, Taste or Smell sensitivities • 9% Autism Spectrum Disorder But aren’t most of these symptoms Autism? Lyme Times, 2005 Summer Edition

10. More research and awareness is on the way.. • Lyme-Autism study in progress through Utah State – grant provided by The Turn the Corner Foundation. • Plans for herbal treatment study. • Educational seminars, online groups, website, articles, parent mentors, conferences, physicians training and think tanks to educate parents and physicians. Don’t leave these children in the dark. With autism at epidemic proportions, parents need your support now. www.liafoundation.org A 501c3 non-profit public benefit charity