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Class Topics

Review Chapter 8 Test NEXT TIME! Inbreeding article Notes – Chapter 9 "Whenever you are asked if you can do a job, tell 'em, 'Certainly I can!' Then get busy and find out how to do it." Theodore Roosevelt. To assess learning about Chapter 8. Title: Biology 3/6/07. Class Topics.

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Class Topics

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  1. Review Chapter 8 Test NEXT TIME! Inbreeding article Notes – Chapter 9 "Whenever you are asked if you can do a job, tell 'em, 'Certainly I can!' Then get busy and find out how to do it." Theodore Roosevelt To assess learning about Chapter 8. Title: Biology 3/6/07 Class Topics Objectives: Monday, January 6, 20207:28 AM

  2. Class Assignments What By When • Read 207-214 3/6/07 • W.S. 9.1 3/8/07 • Due this class period • Due next class period • Due in the future

  3. Grade Sheet 2A – p. 157 (5 pts.)

  4. Review Magazine article “Go ahead and kiss your cousin” • Why are neural degenerative diseases 8 times more common in Bradford than the rest of the UK? (62) • What are lethal alleles (62)? • Why is it likely that 80% of marriages in history were between 2nd cousins or closer? (62) • Why would some rich families encourage cousin marriages? (63) • Why do some cases of inbreeding lead to many diseases while others do not? (63) • What is outbreeding? (64) • What are some problems with outbreeding? (64)

  5. Johann Friedrich Miescher • 1868 - first scientist to isolate DNA • Studied pus from wounds • Called DNA - nuclein • Accomplishment not acknowledged at the time

  6. Frederick Griffith • working on vaccine for pneumonia (1928) • Strains • Smooth (IIIS) - virulent • Rough (IIR) - avirulent

  7. Graphic taken from the MIT Hypertext

  8. From: http://ribonode.ucsc.edu/HuGen/01_80H/01_80Hlec6.html

  9. Transformation • Something changed the IIR strain to the IIIS strain. What was it? • Transformation is the process of changing one form of bacteria into another form • trading genetic information • Between dead (HKIIIS) and living IIR

  10. Griffith’s experiment • Problem • Hypothesis • Procedure • Conclusion • Transformation

  11. Historical Perspective • Genetic material • Believed to be protein • More complex than nucleic acids • More common than nucleic acids

  12. Avery and Co.McCarty & MacLeod • 1944 - took Griffith’s experiment one step farther • found out what had caused transformation • Used enzymes to breakdown organic molecules - Carbohydrase, Protease, Ribonuclease, and Deoxyribonuclease

  13. Avery’s conclusion • Lipase didn’t block transformation • Carbohydrase didn’t block transformation • Protease didn’t block Transformation • Ribonuclease didn’t block transformation • Deoxyribonuclease blocked transformation • What’s the conclusion? • DNA is the genetic material of bacteria

  14. Avery’s experiment • Problem • Hypothesis • Procedure • Conclusion

  15. From: http://ribonode.ucsc.edu/HuGen/01_80H/01_80Hlec6.html

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