Skin infections
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Skin Infections. General Information. Primary interface between body & environment • Protects from chemical/microbial agents &thermal/mechanical trauma • Prevents excess loss of protein, ectrolytes, water & heat • One of largest organs (16% body weight). Normal Flora.

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General information
General Information

  • Primary interface between body & environment

    • Protects from chemical/microbial agents &thermal/mechanical trauma

    • Prevents excess loss of protein, ectrolytes, water & heat

    • One of largest organs (16% body weight).


Normal flora
Normal Flora

Staphylococcus epidermidis

Micrococci

Anaerobic cocci

Diphtheroids

Propionibacterium acnes


Main bacterial diseases
Main Bacterial Diseases

  • Impetigo

  • Scalded skin syndrome (SSS)

  • Erysipelas

  • Cellulites

  • Furuncles

  • Wounds

  • Bites Human

  • Bites Animals

  • Bites Vector

  • Faciitis


Impetigo
Impetigo

  • Impetigo is caused primary by S. pyogenes (Group A) and Staphylococcus aureus.

  • The initial lesion is usually around the mouth or nose. Characterized by small vesicles with a honey-colored crust

  • Diagnosis is usually clinical.


Scalded skin syndrome
Scalded Skin Syndrome

  • Caused by exfoliation producing S. aureus.

  • Results in wide spread exfoliation.

  • Toxin is produced at a local site of infection (usually skin), is carried by the blood to reminder of the epidermis where it causes extensive exfoliation

  • Diagnosed clinically.


Cellulites
Cellulites

  • This is an acute spreading infection of the subcutaneous layer of the skin.

  • Occurs as a result of local infection or trauma.

  • Diagnosed clinically.

  • Can be accompanied by fever, chill and malaise.

  • May lead to septicemia


Furuncles
Furuncles

  • S. aureus can infects a sebaceous gland and forms a small abscess in the subcutaneous tissue.

  • Single abscess= furuncle (boil), multiple= carbuncle.


Faciitis
Faciitis

  • Rapidly progressing cellulites with extensive necrosis of subcutaneous tissues and extension into facia (connective tissue) is caused by the toxin producing organisms: C. perfringens. And S. pyogenes (group A).

  • Both organisms are introduced through trauma.


Acne

  • Formed due to blockage of sebaceous openings and hormonal imbalance during adolescence.

  • C. acne is the main causative agent.


Diabetic foot
Diabetic Foot

  • Infections are usually polymicrobial, including;

    ---S. aureus --- Enterococcus species.

    ---members of the enterobacteriace

    Infections begin after local trauma, usually leading to cellulites.


Wounds
Wounds

  • Clostridium perfringens.

  • Clostridium tetani.



Bites animal
Bites (animal)

  • Pasteurella multocida.


Infected burns
Infected burns

  • Usually by S. aureus, E. coli, klelbsilla, Pseudomonas.


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