Journey through the GI tract. Barb Bancroft, RN, MSN www.barbbancroft.com [email protected] Open wiiiiiiide…. Let’s take a journey through the GI tract with a few stops along the way…. The Teeth. Tooth loss and heart disease
Swollen lips, pharyngeal edema
Hives around the mouth
Highest risk patients?
Don’t forget the cough…
Drugs discovered because of a bite—Brazilian pit viper
Lisinopril (Prinivil, Zestril)
Diabetics, HBP, CHF, post-MI)ACE inhibitors and angioedema
How many times do you swallow in an hour? (70/200/10)
Swallowing is something we take for granted…spit in a cup!
Swappin’ saliva…chemistry? MHC complexSpeaking of saliva…
H+, Intrinsic Factor-B12
PPIs work here
H2 blockers work here
HIGH RISK GROUPS—primary factors
pulmonary toxicity, hypotension, and cardiac arrhythmias, (TSH). Avoid using Amiodarone in patients who may not understand the toxic potential of this interaction.
Word o’ the day…
Omphaloskepsis (om-fuh-lo-SKEP-sis); noun
--Clifton Meador, M.D
Aspirin and polyps- increase the risk for toxicity-38% of those taking an 81.5 mg (low-dose aspirin) had a new polyp compared to 47% in the placebo group. This is a risk reduction of 9%. Now, this isn’t a jaw-dropping difference however, IF colon cancer is a high risk in your family or in a specific patient population, a low-dose aspirin might give you an edge against the disease. (April 2001, American Association of Cancer Research meeting, San Francisco)
a) focal weakness in the colonic wall
b) increased intraluminal pressure