Ion channels defined
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Ion Channels defined. Literature Grows. Early Models. KcsA K channel structures. Gulbis structure. 3 Kinds of nervous signal. AP recording. HH AP. Single Na Channels. State diagram for Na Ch. Early Models. Ion channel disease 1. Ion channel disease 2. Ionic current moving ions.

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Ion Channels defined

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Ion channels defined

Ion Channels defined


Literature grows

Literature Grows


Early models

Early Models


Kcsa k channel structures

KcsA K channel structures


Gulbis structure

Gulbis structure


3 kinds of nervous signal

3 Kinds of nervous signal


Ap recording

AP recording


Hh ap

HH AP


Single na channels

Single Na Channels


State diagram for na ch

State diagram for Na Ch


Early models1

Early Models


Ion channel disease 1

Ion channel disease 1


Ion channel disease 2

Ion channel disease 2


Ionic current moving ions

Ionic current moving ions


Ludwig boltzmann

Ludwig Boltzmann

Question:

How is the internal energy in a system containing a large number of particles (N) distributed among the particles?

Ans.:there will be more particles with low energy (U) than with high

Boltzmann constant

(R/Na )

N

N(U) = A exp -(U/ kbT)

n1

n2

U

U1

U2


Biophysics nernst potential

Biophysics: Nernst Potential


Current voltage relations

Current-Voltage Relations

E is potential in volts


Membrane capacitance

Membrane Capacitance


Equivalent circuits

Equivalent Circuits


Ap recording1

AP recording


Flux coupling in a long pore

Flux coupling in a long pore

Force


Kcsa k channel structures1

KcsA K channel structures


Stoichiometry of a pump

Na:K ATPase, a Stoichiometric Transporter

Moves 3Na+ out and 2K+ in per ATP.

Stoichiometry of a pump


Evolutionary tree

Evolutionary tree


K channel dendrogram

K Channel Dendrogram


Three roles of ion channels

Three Roles of ion channels


Electrical call to action

Electrical call to action


Ca channel modulation

Ca channel modulation


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