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Snail

Suppl. Fig. 1. B. A. + - - -. DMSO. EP4Ra ( μ M). - - + +. EP4R inhibitor. 0.1. 1. 5. 10. - + - +. 0. PGE 2. Snail. Snail. β -actin. β-actin. D. C. (min). EP4Ra 0 30 45 60 (min). 0. 15. 30. 60.

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Snail

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  1. Suppl. Fig. 1 B A + - - - DMSO EP4Ra (μM) - - + + EP4R inhibitor 0.1 1 5 10 - + - + 0 PGE2 Snail Snail β-actin β-actin D C (min) EP4Ra 0 30 45 60 (min) 0 15 30 60 EP4Ra p-EGFR (Tyr1173) p-Akt (Thr308) Akt (total) EGFR (total) F E DMSO + - - - DMSO + - - - LY294002 - - + + PDTC - - + + EP4Ra - + - + EP4Ra - + - + p-P65 Snail P65 β-actin

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